Urinary pH and Calcium Oxalate Crystallization

  • H.-G. Tiselius
Conference paper
Part of the Fortschritte der Urologie und Nephrologie book series (2824, volume 22)


Previous studies have shown that, whereas urinary pH is of limited importance for the ion activity product and solubility of calcium oxalate, crystals of calcium oxalate are rare in alkaline urine (Hallson and Rose 1978; Gregory et al. 1981; Gregory 1981). Furthermore, it was observed that the inhibition of calcium oxalate crystal growth in diluted urine was increased at high pH values (Tiselius 1981). Information on the crystallization of calcium oxalate in whole urine is scanty, and the present study was undertaken in order to get information on how calcium oxalate precipitates in urine which is supersaturated with calcium oxalate at different pH levels.


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  1. 1.
    Butz, M.: Oxalatsteinprophylaxe durch Alkali-Therapie. Urologe A 21: 142–146 (1982).PubMedGoogle Scholar
  2. 2.
    Gregory, J. G., Hoy, M. M., Park, K. I., Feigl, A.: The effect of urinary pH on the saturation of calcium and oxalate and on urinary crystal formation, pp. 489–492. In: Smith, L. H., Robertson, W. G., Finlayson, B. (eds.) Urolithiasis-clinical and basic research. Plenum, New York (1981).Google Scholar
  3. 3.
    Gregory, J. G.: Hyperoxaluria and stone disease in gastrointestinal bypass patients. Urologic Clinics of North America 8: 331–351 (1981).PubMedGoogle Scholar
  4. 4.
    Hallson, P. C, Rose, G. A.: A new urinary test for stone “activity”. British Journal of Urology 50: 442–448 (1978).PubMedCrossRefGoogle Scholar
  5. 5.
    Nielsen, A. E.: Kinetics of precipitation. International series of monographs on analytical chemistry, vol. 18. Pergamon, Oxford (1968).Google Scholar
  6. 6.
    Sakhaee, K., Nicar, M., Jacobson, H., Pak, C. Y. C: Potassium alkali therapy of uric acid lithiasis may prevent complication of calcium stones. Clinical Research 30: 403 A (1982).Google Scholar
  7. 7.
    Tiselius, H.-G.: The effect of pH on the urinary inhibition of calcium oxalate crystal growth. British Journal of Urology 53: 470–474 (1981).PubMedCrossRefGoogle Scholar

Copyright information

© Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG., Darmstadt 1984

Authors and Affiliations

  • H.-G. Tiselius
    • 1
  1. 1.Department of UrologyUniversity HospitalLinköpingSweden

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