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Prophylactic treatment of renal stone disease with magnesium hydroxide during five years

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Pathogenese und Klinik der Harnsteine IX

Part of the book series: Fortschritte der Urologie und Nephrologie ((2824,volume 20))

Abstract

Already in the year 1810 (Brande) was magnesium proposed as prophylactic treatment against renal stone disease. It was later shown that magnesium increased the solubility of calcium oxalate in vitro (Hammarsten, 1929). Desmars and Tawashi (1973) demonstrated the greater solubility product for magnesium oxalate than for calcium oxalate and magnesium has also been found to account for 20% of the total inhibitory activity of calcium phosphate precipitation in whole urine (Bisaz et al., 1978).

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References

  1. de Albuquerque, P. F., Tuma, M.: Investigations on urolithiasis. II: Studies on oxalate. J. Urol. 87: 504 (1962).

    Google Scholar 

  2. Bisaz, S., Felix, R., Neumann, W. F., Fleisch, H.: Quantitative determination of inhibitors of calcium phosphate precipitation in whole urine. Mineral Electrolyte Metab. 1: 74 (1978).

    CAS  Google Scholar 

  3. Brande, W. T.; Observations on the effects of magnesia in preventing an increased formation of uric acid; with some remarks on the composition of urine. Med. Phys. J. 24: 203 (1810).

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  4. Danielson, B. G., Johansson, G., Ljunghall, S.: Magnesium metabolism in healthy subjects. Scand. J. Urol. Nephrol. 51 (suppl): 49 (1979).

    Google Scholar 

  5. Desmars, J. F., Tawashi, R.: Dissolution and growth of calcium oxalate monohydrate. I. Effect of magnesium and pH. Biochim. Biophys. Acta 313: 256 (1973).

    Article  PubMed  CAS  Google Scholar 

  6. Gershoff, S. N., Prien, E. L.: Effect of daily MgO and vitamin B6 administration to patients with recurring calcium oxalate kidney stones. Am. J. Clin. Nutr. 20: 393 (1967).

    PubMed  CAS  Google Scholar 

  7. Hammarsten, G.: On calcium oxalate and its solubility in the presence of inorganic salts with special reference to the occurrence of oxaluria. C R Lab. Carlsberg 17: 1 (1929).

    Google Scholar 

  8. Johansson, G., Backman, U., Danielson, B. G., Ljunghall, S., Wikström, B.: Magnesium metabolism in renal stone disease. Invest. Urol. 18: 93 (1980a).

    PubMed  CAS  Google Scholar 

  9. Johansson, G., Backmann, U., Danielson, B. G., Fellström, B., Ljunghall, S., Wikström, B.: Biochemical and clinical effects of the prophylactic treatment of renal calcium stones with magnesium hydroxide. J. Urol. 124: 770 (1980b).

    PubMed  CAS  Google Scholar 

  10. Johansson, G., Backman, U., Danielson, B. G., Fellström, B., Ljunghall, S., Wikström, B.: Prophylactic treatment with magnesium hydroxide in renal stone disease. In: Urolithiasis: Clinical and basic research. (Ed. L. H. Smith ), pp 267–274. Plenum Publishing Corporation, 1981.

    Google Scholar 

  11. Wikström, B., Backman, U., Danielson, B. G., Fellström, B., Johansson, G., Ljunghall, S.: Urinary citrate excretion and acidification defects in renal calcium stone formers. In: Urolithiasis: Clinical and basic research. (Ed. L. H. Smith ), pp 757–762. Plenum Publishing Corporation, New York, 1981.

    Google Scholar 

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© 1982 Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt

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Johansson, G., Backman, U., Danielson, B.G., Fellström, B., Ljunghall, S., Wikström, B. (1982). Prophylactic treatment of renal stone disease with magnesium hydroxide during five years. In: Gasser, G., Vahlensieck, W. (eds) Pathogenese und Klinik der Harnsteine IX. Fortschritte der Urologie und Nephrologie, vol 20. Steinkopff. https://doi.org/10.1007/978-3-642-72360-5_59

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  • DOI: https://doi.org/10.1007/978-3-642-72360-5_59

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-7985-0608-4

  • Online ISBN: 978-3-642-72360-5

  • eBook Packages: Springer Book Archive

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