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The interaction of urinary inhibitors with crystals

  • B. Fellström
  • U. Backman
  • B. G. Danielson
  • K. Holmgren
  • S. Ljunghall
  • B. Wikström
Conference paper
Part of the Fortschritte der Urologie und Nephrologie book series (2824, volume 20)

Abstract

It has been proposed that hyperuricosuria may promote calcium oxalate stone formation. One of the suggested mechanisms is an interference between urate microcrystals and naturally occurring macromolecular inhibitors of crystal growth and aggregation (1). Furthermore, it has been shown in vitro that sodium urate crystals may absorb heparin, a potent inhibitor of calcium oxalate crystallisation (2). As heparin is not excreted in human urine other than in minute amounts we decided to study the interference between naturally occurring urinary inhibitors and various crystals.

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References

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Copyright information

© Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt 1982

Authors and Affiliations

  • B. Fellström
    • 1
  • U. Backman
    • 1
  • B. G. Danielson
    • 1
  • K. Holmgren
    • 2
  • S. Ljunghall
    • 1
  • B. Wikström
    • 1
  1. 1.Department of Internal MedicineUniversity HospitalUppsalaSchweden
  2. 2.Department of UrologyUniversity HospitalUppsalaSchweden

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