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Direkte Aktivierung von C3

Der sog. Nebenschluβ

  • Chapter
Komplement

Zusammenfassung

Die vorangehende Darstellung der C-Reaktionssequenz bei der Immunhämolyse ging von dem historisch gewachsenen Konzept aus. Bis vor wenigen Jahren war man überzeugt, daß allein die Aktivierung von C1 durch Ag-Ak-Komplexe die C-Reaktion in Gang setzen kann, und daß nur über eine C1-Aktivierung auch die anderen Komponenten aktiviert werden können. Wir wissen heute, daß dieser Zugang zur C-Reaktion und ihren biologischen Auswirkungen nur einer von mehreren ist und vielleicht nicht einmal der bedeutendste.

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Rother, K. (1974). Direkte Aktivierung von C3. In: Rother, K. (eds) Komplement. Steinkopff. https://doi.org/10.1007/978-3-642-72310-0_4

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