Results

  • D. N. Angelov
  • M. Walther
  • W. F. Neiss
  • M. Streppel
  • O. Guntinas-Lichius
Part of the Advances in Anatomy Embryology and Cell Biology book series (ADVSANAT, volume 147)

Abstract

The following results are presented in five sections:
  • Section 3.1 will show that the lesion model used, i.e., the resection of 10 mm of the infratemporal portion of the facial nerve, fully inhibits post-operative axonal sprouting and causes a delayed, but significant loss of neurons in the facial nucleus.

  • Section 3.2 provides evidence that the neuronal death caused by resection of the facial nerve does not lead to a breakdown of the blood-brain barrier and that there occurs no passage of unprimed lymphocytes into the brain tissue.

  • Section 3.3 describes the different patterns of cell labeling with the permanent tracer Fluoro-Gold (FG) after its intramuscular, intravenous, and intracerebroventricular (ICV) injection.

  • Section 3.4 covers our quantitative and qualitative estimates on the time course of existence and migration of FG-labeled neuronophages.

  • Section 3.5 shows the time course of expression of immune related antigens by FG-labeled neuronophages. It provides evidence that perivascular cells migrate from the perivascular space into perineuronal position and, like the microglia, carry out neuronophagia. Finally, Sect. 3.5 shows that after neuronophagia, perivascular cells — but not microglia — return to the perivascular space.

Keywords

Permeability Migration Toxicity Sine Eosin 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • D. N. Angelov
    • 1
  • M. Walther
    • 1
  • W. F. Neiss
    • 1
  • M. Streppel
    • 2
  • O. Guntinas-Lichius
    • 2
  1. 1.Institut für Anatomie der Universität zu KölnKölnGermany
  2. 2.Klinik für Hals-, Nasen- und Ohrenheilkunde der Universität zu KölnKölnGermany

Personalised recommendations