• A. E. Frankel
  • M. C. Willingham
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 234)


The targeted toxin research reviewed in this volume includes recent advances in clinical applications of these compounds. The observation of clinical efficacy of both transferrin conjugated to mutant diphtheria toxin in high-grade gliomas and truncated diphtheria toxin fused to interleukin-2 in cutaneous T cell lymphomas and psoriasis are achievements for which all the members of the targeted toxin research community can be proud. The participation of so many colleagues in this field in this book has been a reflection both of the kindness and friendliness of the individuals as well as their commitment to working together to develop a new class of human therapeutics.


Diphtheria Toxin Large Granular Lymphocyte Fusion Toxin Pokeweed Antiviral Protein Vascular Leak Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • A. E. Frankel
    • 1
  • M. C. Willingham
    • 1
  1. 1.Hollings Cancer CenterCharlestonUSA

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