Abstract
The rodent organ transplant model has become increasingly popular. The oldest model is perhaps the nonvascularized skin graft [1]. There are, however, several limitations with this model: (a) the immune response of nonvascularized grafts is different from vascularized grafts; (b) pathological study is difficult once the skin graft is rejected; and (c) self-mutilation of grafts is a problem. Vascularized graft models have been developed for heart, kidney, liver, and small intestine in both rats and mice [2–9]. Aside from the technical difficulties, graft function can be difficult to monitor postoperatively and biopsy of the graft is not usually possible.
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© 1998 Springer-Verlag Berlin Heidelberg
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Jiang, J., Humar, A., Zhong, R. (1998). Surgical Technique for Vascularized Ear Transplantation in Mice. In: Timmermann, W., Gassel, HJ., Ulrichs, K., Zhong, R., Thiede, A. (eds) Organtransplantation in Rats and Mice. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72140-3_19
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DOI: https://doi.org/10.1007/978-3-642-72140-3_19
Publisher Name: Springer, Berlin, Heidelberg
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