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TMLR Management of Coronary Artery Diseases pp 99–108Cite as

Borderline Indications for Heart Transplantation and Alternative Measures

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Abstract

At the present time, approx. 1–2% of the population of the Western world contract cardiac insufficiency, usually therapy-resistant and terminal. Orthotopic heart transplantation (HT) represents the only currently available curative form of therapy with a justifiable 5-year survival prognosis (Ref. 12). The growing mismatch between donor pool and recipient group has provoked constant discussion about the criteria for inclusion and exclusion in these groups (Refs. 18, 28). Whereas in the initial stages of HT recipient age and concomitant diseases were crucial criteria for recipient selection, improved chances of survival caused these criteria to be relaxed (Ref. 12). Biological age is becoming more and more predominant in the selection of recipients. Concomitant diseases, such as diabetes mellitus, hepatitis B/C, secondary amyloidosis, condition following neoplasia beyond the 5-year recurrence rate no longer represent contraindications (Refs. 23, 26, 16, 17). Current contraindications for orthotopic HT include fixed pulmonary hypertension (>5 Wood units), active acute infections and HIV infections.

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Authors
  1. M. M. Koerner
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  2. G. Tenderich
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  3. R. Koerfer
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Editors and Affiliations

  1. Klinik für Thorax- und Kardiovaskuläre Chirurgie, Heinrich-Heine-Universität, Moorenstraße 5, D-40225, Düsseldorf, Germany

    Michael Klein , H. D. Schulte  & E. Gams ,  & 

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© 1998 Springer-Verlag Berlin Heidelberg

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Koerner, M.M., Tenderich, G., Koerfer, R. (1998). Borderline Indications for Heart Transplantation and Alternative Measures. In: Klein, M., Schulte, H.D., Gams, E. (eds) TMLR Management of Coronary Artery Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72134-2_8

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  • DOI: https://doi.org/10.1007/978-3-642-72134-2_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72136-6

  • Online ISBN: 978-3-642-72134-2

  • eBook Packages: Springer Book Archive

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