Abstract
Transmyocardial laser revascularisation (TMR) is a novel therapeutic approach to ischaemic heart disease. It was originally based on investigations carried out in the 1950s and 1960s aimed at simulating the reptilian concept of sinusoidal myocardial perfusion by needle acupuncture [1–3]. With TMR, finely focused lasers perforate areas of ischaemic myocardium, creating transmyocardial channels [4, 5]. Experimental data suggest that within months, these transmyocardial channels may stimulate new vessel growth in the previously ischaemic region [6, 7]. Encouraging clinical effects have been seen in various multicenter studies: relief from angina, increased myocardial perfusion, and reduced frequency of costly hospitalisation for recurrent angina [8–10].
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© 1998 Springer-Verlag Berlin Heidelberg
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Seitelberger, R., Wild, T., Wolfram, J. (1998). Transmyocardial Laser Revascularisation with a Holmium:YAG Laser: Initial Clinical Experience. In: Klein, M., Schulte, H.D., Gams, E. (eds) TMLR Management of Coronary Artery Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72134-2_19
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DOI: https://doi.org/10.1007/978-3-642-72134-2_19
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