Pouch pp 441-446 | Cite as

Onkologische Aspekte der chirurgischen Therapie der Colitis ulcerosa

  • U. Heuschen
  • G. Heuschen
  • J. Stern
  • C. Herfarth
Conference paper

Zusammenfassung

Die Colitis ulcerosa (CU) stellt bekanntermaßen eine Risikoerkrankung für colorektale Karzinome dar. Allgemein anerkannte Risikofaktoren sind: die Ausdehnung der CU, die Dauer der Erkrankung und der Beginn im Kindesalter [1–4]. Dysplastische Epithelveränderungen gelten im Sinne einer Colitis-Dysplasie-Karzinom-Sequenz als präkanzeröse Läsionen [5–7]. Aus onkologischer Sicht wäre es daher wünschenswert, wenn eine chirurgische Therapie nicht erst bei einem manifesten Colitis-Karzinom, sondern prophylaktisch durchgeführt würde. Durch eine prophylaktische Proktokolektomie mit ileoanaler Pouchoperation können wir dem Patienten ein Verfahren anbieten, mit dem sich 3 Ziele verwirklichen lassen [8, 9]:
  1. 1.

    Sanierung der colorektalen Colitis ulcerosa-Manifestation.

     
  2. 2.

    Beseitigung des Entartungsrisikos im Colorektum.

     
  3. 3.

    Kontinenzerhalt mit guter Lebensqualität.

     

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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • U. Heuschen
  • G. Heuschen
  • J. Stern
  • C. Herfarth

There are no affiliations available

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