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Mapping the Organic and Inorganic Components of Bone

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X-Ray Microscopy and Spectromicroscopy

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Abstract

A mapping technique which uses a scanning transmission soft X-ray microscope (STXM) is described. The technique has been developed and used to quantitatively map the calcium mineral and protein mass thicknesses in undemineralised, unstained, thin bone sections. Near complete femoral-neck sections of sibling normal and ovariectomised mice have been mapped. The results show the quantitative relationship between calcium and protein on the macro and microscopic scales for both tissues.

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Author information

Authors and Affiliations

  1. Department of Physics, King’s College London, Strand, London, WC2R 2LS, UK

    C. J. Buckley, N. Khaleque & S. J. Bellamy

  2. Department of Physiology, King’s College London, Strand, London, WC2R 2LS, UK

    M. Robins

  3. Department of Physics, State University of New York, Stony Brook, NY, 11794, USA

    X. Zhang

Authors
  1. C. J. Buckley
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  2. N. Khaleque
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  3. S. J. Bellamy
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  4. M. Robins
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  5. X. Zhang
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Editor information

Editors and Affiliations

  1. Forschungseinrichtung Röntgenphysik, Georg-August-Universität Göttingen, Geiststrasse 11, D-37073, Göttingen, Germany

    Jürgen Thieme , Günter Schmahl  & Dietbert Rudolph ,  & 

  2. Experimentelle Physik II, Universität Würzburg, Am Hubland, D-97074, Würzburg, Germany

    Eberhard Umbach

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© 1998 Springer-Verlag Berlin Heidelberg

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Buckley, C.J., Khaleque, N., Bellamy, S.J., Robins, M., Zhang, X. (1998). Mapping the Organic and Inorganic Components of Bone. In: Thieme, J., Schmahl, G., Rudolph, D., Umbach, E. (eds) X-Ray Microscopy and Spectromicroscopy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72106-9_16

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  • DOI: https://doi.org/10.1007/978-3-642-72106-9_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72108-3

  • Online ISBN: 978-3-642-72106-9

  • eBook Packages: Springer Book Archive

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