Hemodynamic Management of Gastric Intramucosal Acidosis in Septic Patients

  • E. Silva
  • D. De Backer
  • J.-L. Vincent
Conference paper
Part of the Yearbook of Intensive Care and Emergency Medicine book series (YEARBOOK, volume 1998)


Although sepsis is typically characterized by normal or increased systemic blood flow and decreased oxygen extraction [1], regional hypoperfusion and tissue hypoxia may be present [2]. Systemic parameters currently monitored during resuscitation may not reflect regional blood flow abnormalities and ongoing hypoperfusion in specific organ system beds may lead to subsequent organ failure even when global blood flow is restored or increased [3–5]. A logical approach is to focus on assessment of regional oxygenation. Gastric tonometry is a possible tool to assess gastric perfusion. However, we need to understand better the meaning of a high gastric mucosal carbon dioxide tension (PCO2) or a low gastric intramucosal pH (pHi) to adequately interpret studies assessing hemodynamic management guided by these measurements.


Septic Shock Septic Patient Respir Crit Septic Shock Patient Endotoxic Shock 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • E. Silva
  • D. De Backer
  • J.-L. Vincent

There are no affiliations available

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