Abstract
The aim of antibiotic treatment is to cure infection, documented or not, while fulfilling, if possible, certain conditions: The lowest risk of toxicity; the lowest cost; and the least impact on bacterial ecology in order to limit the emergence of resistant strains.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Moellering RC (1985) Can the third-generation cephalosporins eliminate the need for antimicrobial combinations? Am J Med (suppl 2A ): 104–109
Eliopoulos GM, Moellering BC (1991) Antimicrobial combinations. In: Lorian V (ed) Antibiotics in laboratory medicine. Williams and Wilkins Co, Baltimore, pp 432–492
Denis JP, Gouin (1992) Association d’antibiotiques In: Martin C, Gouin F (eds) Antibiothérapie en réanimation et en chirurgie. Arnette, Paris, pp 351–362
Dejace P, Klatersky J (1986) Comparative review of combination therapy: two beta-lactams versus beta-lactam plus aminoglycoside. Am J Med 80 (suppl. 6B): 29–37
Barriere SL (1991) Monotherapy versus combination antimicrobial therapy. A review. Pharma-cotherapy 11: 645–654
Joly-Guillou ML, Bergogne-Berezin E (1986) Synergies ou antagonismes des associations d’anti-biotiques. Presse Med 15: 1037–1040
Regnier B (1987) Utilisation des associations d’antibiotiques. Presse Med 16: 2186–2191
Martin C, Perrin G, Lambert D (1992) Les quinolones. In: Martin C, Gouin F (eds) Antibiothérapie en réanimation et en chirurgie. Arnette, Paris, pp 109–112
Martin C, Gouin F, Fourrier F, Juninger W, Prieur BL (1988) Pefloxacin in the treatment of noso-comial lower respiratory tract infections in intensive care patients. J Antimicrob Chemother 21: 795–799
Pechere JC, Marchou B, Michea-Hamlehpour M, Aukenthaler A (1986) Emergence of resistance after therapy with antibiotics used alone or combined in a murine model. J Antimicrob Chemother 17 (suppl A) 11–18
Michea-Hamzehpour M, Pechere JC, Marchou B, Auckenthaler RC (1986) Combination therapy: a way to limit the emergence of resistance. Am J Med 80 (suppl 6B): 138–142
Boogaerts MA (1995) Anti-infective strategies in neutropenia. J Antimicrob Chemother 36 (suppl A): 167–178
Perronne C, Regnier B, Legrand P, et al (1986) Echec des nouvelles béta-lactamines dans le traitement d’infections sévères Enterobacter cloacae. Presse Med 15: 1813–1818
Anonymous (1991): Respiratory infections of the lower respiratory airway. 4th Consensus Conference of the French Society of Infectious Diseases. Med Mai Inf 21 (suppl 1): 1–8
Niederman MS, Bass JB, Campbell GD, et al (1993) Guidelines for the initial management of adults with community-acquired pneumonia: diagnosis, assessment of severity, and initial antimicrobial therapy. Am Rev Respir Dis 142: 1418–1426
American Thoracic Society (1995) Hospital-acquired pneumonia in adults: diagnosis, assessment of severity, initial antimicrobial therapy, and preventive strategies. Am J Respir Crit Care Med 143: 1711–1725
Bohnen JMA, Solomkin JS, Dellinger EP, Bjornson S, Page CP (1992) Guidelines for clinical care: anti-infective agents for intra-abdominal infections. Arch Surg 127: 83–89
Geroulanos SJ and the Meropenem Study Group (1995) Meropenem versus imipenem/cilastatin in intra-abdominal infections requiring surgery. J Antimicrob Chemother 36 (suppl A): 191–205
Huizinga WKJ, Warren BL, Baker LW, et al (1995) Antibiotic monotherapy with meropenem in the surgical management of intra-abdominal infections. J Antimicrob Chemother 36 (suppl A): 79–89
Cometta A, Baumgartner JD, Lew D, et al (1994) Prospective randomized comparison of imipenem monotherapy with imipenem plus netilmicin for the treatment of severe infections in non- neutropenic patients. Antimicrob Agents Chemother 38: 1309–1313
Winston DJ, Mc Grattan MA, Busuttil RW (1984) Imipenem therapy of Pseudomonas aeruginosa and other serious bacterial infections. Antimicrob Agents Chemother 26: 673–677
Croce MA, Fabian TC, Stewart RM, et al (1993) Empiric monotherapy versus combination therapy of nosocomial pneumonia in trauma patients. J Trauma 35: 303–309
Solberg CO, Sjursen H (1995) Safety and efficacy of meropenem in patients with septicemia: a randomised comparison with ceftazidime, alone or combined with amikacin. J Antimicrob Chemother 36 (suppl A): 157–166
Norrby SR, Finch RG, Glauser M, et al (1993) Monotherapy of serious hospital-acquired infections: a clinical trial of ceftazidime versus imipenem/cilastatin. J Antimicrob Chemother 31: 927–937
Cometta A, Calandra T, Gaya H, et al (1996) Monotherapy with ceftazidime plus amikacin as empiric therapy for fever in granulocytopenic patients with cancer. Antimicrob Agents Chemother 40: 1108–1115
Leibovici L, Paul M, Poznanski O, et al (1997) Monotherapy versus ß-lactam-aminoglycoside combination treatment for Gram-negative bacteremia: a prospective, observational study. Anti-microb Agents Chemother 41: 1127–1133
Martin C (1992) Rapports thérapeutiques (taux tissulaires/CMI 90). In: Martin C, Gouin F (eds) Antibiothérapie en réanimation et en chirurgie. Arnette, Paris, pp 717–741
Fantin B, Carbon C (1992) In vivo antibiotic synergism: contribution of animal models. Anti-microb Agents Chemother 36: 907–912
Mallet MN (1992) Bactériostase, bactéricidie, étude des associations d’antibiotiques. In: Martin C, Gouin F (eds) Antibiothérapie en réanimation et en chirurgie. Arnette, Paris, pp 281–304
Kaatz GW, Seo SM, Barriere SL, Albrecht LM, Rybak MJ (1989) Ciprofloxacin and rifampin, alone and in combination, for therapy of experimental Staphylococcus aureus endocarditis. Anti-microb Agents Chemother 33: 1184–1187
Acar JF, Goldstein FW, Duval J (1983) Use of rifampin for the treatment of serious staphylococcal and gram-negative bacillary infections. Rev Infect Dis 5 (suppl 3): 502–506
Bayer AS, Lam KJ (1985) Efficacy of vancomycin plus rifampicin in experimental aortic valve - endocarditis due to methicillin-resistant Staph aureus: in vitro — in vivo correlations. J Infect Dis 151: 157–165
Norden CW, Shaffer M (1983) Treatment of experimental chronic osteomyelitis due to Staphylococcus aureus with vancomycin and rifampin. J Infect Dis 147: 352–357
Wispelwey B, Scheid WM (1990) Brain abcess. In: Mandell GL, Douglas RG, Bennett JE (eds) Principles and practice of infectious diseases. Churchill Livingstone, New York, pp 777–787
Caron F, Carbon C, Gutmann L (1991) Evaluation of the triple combination penicillin-vanco- mycin-gentamicin in an experimental endocarditis caused by moderately penicillin and a highly glycopeptide-resistant strain of Enterococcus faecium. J Infect Dis 164: 888–893
Klatersky J, Zinners SH (1982) Synergistic combinations of antibiotics in Gram-negative bacillary infections. Rev Infect Dis 4: 294–301
Sande MA, Irvin RG (1975) Penicillin-aminoglycoside synergism in experimental Streptococcus vidans endocarditis. J Infect Dis 136: 327–335
Sande MA, Courtney KB (1976) Nafcillin-gentamicin synergism in experimental staphylococcal endocarditis. J Lab Clin Med 88: 118–124
Wilson WR (1987) Antimicrobial therapy of streptococcal endocarditis. J Antimicrob Chemother 20 (suppl A): 147–159
Henry NK, Wilson WR, Geraci JE (1986) Treatment of streptomycin-susceptible enterococcal experimental endocarditis with combinations of penicillin and low- or high-dose streptomycin. Antimicrob Agents Chemother 30: 725–728
Levine DP, Cushing RD, Jui J, Brown WJ (1982) Community-acquired methicillin-resistant Staphylococcus aureus endocarditis in the Detroit Medical Center. Ann Intern Med 97: 330–338
Korzeniowski O, Sande MA and the NCESG (1982) Combination antimicrobial therapy for Staphylococcus aureus endocarditis in patients addicted to parenteral drugs and in non addicts. Ann Inter Med 97: 496–504
Rahal JJ (1986) Treatment of methicillin-resistant staphylococcal infection. In: Peterson PK, Verhoef J (eds) The antimicrobial agents annual I. Elsevier, Amsterdam, pp 489–514
Reyes MP, Lerner AM (1983) Current problems in the treatment of infective endocarditis due to Pseudomonas aeruginosa. Rev Infect Dis 5: 314–321
Martin C, Saux P, Perrin G (1992) Choix d’une antibiothérapie pour le traitement d’une infection à Pseudomonas. In: Martin C, Gouin F (eds) Antibiothérapie en réanimation et en chirurgie. Arnette, Paris, pp 389–406
Quinn JP, Dubek EJ, Divincenzo CA, Lucks DA, Lerner SA (1986) Emergence of resistance to imipenem during therapy for Pseudomonas infection. J Infect Dis 16: 289–294
Nichols L, Maki DG (1985) The emergence of resistance to beta-lactam antibiotics during treatment of Pseudomonas aeruginosa lower respiratory tract infections: is combination therapy the solution? Chemotherapia 4: 102–109
Martin C, Albanèse J, Thomachot L, Quinio B (1993) Choix d’une antibiothérapie pour le traitement d’une infection staphylocoques. In: Conférences d’actualisation 35e Congrès National d’Anesthésie et Réanimation. Masson, Paris, pp 601–620
Saux P, Martin C, Perrin G (1992) La fosfomycine. In: Martin C, Gouin F (eds) Antibiothérapie en réanimation et en chinurgie. Arnette, Paris, pp 189–194
Chow JW, Fine MJ, Shlaes DM (1991) Enterobacter bacteremia: clinical features and emergence of antibiotic resistance during therapy. Ann Intern Med 115: 585–590
Gribble M J, Chow AW, Naiman SC, et al (1983) Prospective randomized trial of piperacillin monotherapy versus carboxypenicillin-aminoglycoside combination regimens in the empirical treatment of serious bacterial infections. Antimicrob Agents Chemother 24: 388–393
Fink MP, Snydman DR, Niederman MS (1994) Treatment of severe pneumonia in hospitalized patients: results of a multicenter, randomized, double blind trial comparing intravenous ciprofloxacin with imipenem-cilastin. Antimicrob Agents Chemother 38: 547–557
Thabaut A (1992) Imipénème: Monotherapie ou associations? Arguments microbiologiques. Lettre Infect 7: 151–153
Hilf M, Yu VL, Sharp J, et al (1989) Antibiotic therapy for Pseudomonas aeruginosa bacteremia: outcome correlation in a prospective study of 200 patients. Am J Med 87: 540–546
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Viviand, X., Arnaud, S., Martin, C. (1998). Why, When, and How to Prescribe a Combination of Antibiotics. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 1998. Yearbook of Intensive Care and Emergency Medicine, vol 1998. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72038-3_28
Download citation
DOI: https://doi.org/10.1007/978-3-642-72038-3_28
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-63798-1
Online ISBN: 978-3-642-72038-3
eBook Packages: Springer Book Archive