Skip to main content

Natürliche und künstliche Allergene

  • Chapter
Pneumologische Umweltmedizin
  • 95 Accesses

Zusammenfassung

Der Anstieg von allergischen Erkrankungen im Bereich des Hautorganes und der Atemwege hat in den letzten Jahren zu vielen Spekulationen über die Gründe und Ursachen geführt. In diesem Kapitel sollen einige Gedanken und Hypothesen zur Pathogenese vorgestellt werden. Weiterhin solI hier auf Dosis-Wirkungsbeziehungen und inhalative Verursachung von Sensibilisierungen eingegangen werden. Abschließend sollen einige Umwelt- und Arbeitsbereiche exemplarisch vorgestellt werden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Allmers H, Huber H, Baur X (1997) Bronchopulmonale Schimmelpilzallergie eines Müllwerkers. Arbeitsmed Sozialmed Umweltmed 32: 64–67

    Google Scholar 

  2. Allmers H, Kirov A, Hagemeyer O, Huber H, Walther JW, Baur X (1996) Latexsensibilisierung und Latexallergenkonzentration in der Luft. Ergebnis einer Querschnittsuntersuchung in einem Krankenhaus und in Arztpraxen. Allergologie 19: 68–70

    Google Scholar 

  3. Allmers H, Kirchner B, Huber H, Chen Z, Walther JW, Baur X (1996): Latenzzeit zwischen Exposition und Symptomen bei Allergie gegen Naturlatex. Dtsch med Wschr 121: 823–828

    Article  PubMed  CAS  Google Scholar 

  4. Alroth M, Alenius H, Turjanmaas K, Mäkinen-Kiljunen S, Reunala T, Palosuo T (1995) Cross-reacting allergens in natural rubber latex and avocado. J Allergy Clin Immunol 96:167–173

    Article  Google Scholar 

  5. Antó JM, Sunyer J, Taylor Newman AJ (1996) Comparison of soybean epidemic asthma and occupational asthma in Occupational Lung Disease. Thorax 51:743–749

    Article  PubMed  Google Scholar 

  6. Arellano R, Bradley J, Sussman G (1992) Prevalence of latex sensitization among hospital physicians occupationally exposed to latex gloves. Anesthesiology 77: 905–908

    Article  PubMed  CAS  Google Scholar 

  7. Baur X, Allmers H (1996) Berufsbedingte Allergien. Diagnostisches Vorgehen in der Praxis. Praxismagazin med. 3/96 S. 30–35

    Google Scholar 

  8. Baur X, Hahn D, Weiss W (1988) Allergische bronchopulmonale Aspergillose mit heustaubinduzierter Alveolitis und Asthma bronchiale. Dtsch Med W schr 113: 1105

    Article  CAS  Google Scholar 

  9. Baur X (1995) Wirkung von Isocyanaten und anderen niedermolekularen Substanzen auf die Atemwege und das Immunsystem. Atemw Lungenkrkh 4: 184–188

    Google Scholar 

  10. Baur X (1990) Inhalative Allergene und Irritantien am Arbeitsplatz. Allergologie 13; 4:134–139 Sonderdruck aus Allergologie, Dustri Verlag München-Deisenhofen

    Google Scholar 

  11. Bauer X und Mitglieder der interdisziplinären Arbeitsgruppe (1996) Naturlatex-AllergieEmpfehlungen der interdisziplinaren Arbeitsgruppe. Allergologie 19: 248–251

    Google Scholar 

  12. Baur X, Jäger D (1990) Airborne antigens from latex gloves. Lancet 335:912

    Article  PubMed  CAS  Google Scholar 

  13. Baur X, Ammon J, Chen Z, Beckmann U, Czuppon AB (1993) Health risk in hospitals through airborne latex allergens for patients presensitised to latex. Lancet 342: 1148 -1149

    Article  PubMed  CAS  Google Scholar 

  14. Baur X, Chen Z, Allrners H, Beckmann U, Walther JW (1996) Relevance oflatex aeroallergen for healthcare workers. Allergology International 20: 105–111

    Google Scholar 

  15. Berky ZT, Luciano WJ, James WD (1992) Latex glove allergy. A survey of the US Army Dental Corps. J Arner Med A 268: 2695–2697

    CAS  Google Scholar 

  16. Berufskrankheiten-Verordnung (BeKV) vom 8. Dezember 1976, Bundesgesetzblatt I, S. 3329 in der Fassung der Zweiten Verordnung zur Änderung der Berufskrankheiten-Verordnung vom 18. Dezember 1992. Bundesgesetzblatt I, S. 2343

    Google Scholar 

  17. BGA (Bundesgesundheitsamt, Institut für Sozialmedizin und Epidemiologie) (1994) Die Gesundheit der Deutschen. Ein Ost-West-Vergleich. Soz Epi Hefte 4

    Google Scholar 

  18. Blaski CA, Clapp WD, Thorne PS, Quinn TJ, Watt JL, Frees KL, Yagla SJ, Schwartz DA (1996) The Role of Atopy in Grain Dust-Induced Airway Disease. Am J Respir Crit Care Med 154:334–340

    PubMed  CAS  Google Scholar 

  19. Bohadana AB, Massin N, Wild P, Berthiot G (1996) Airflow obstruction in chalkpowder and sugar workers. Arch Occup Environ Health, Springer Verlag, Berlin 68: 243–248

    CAS  Google Scholar 

  20. Bolm Audorff U, Bienfait HG, Albracht G (1996) Staubexposition in Backerbetrieben. Zbl Arbeitsmed 46: 105–110

    Google Scholar 

  21. Brauer M, Kennedy SM (1996) Gas stoves and respiratory health. The Lancet 347:412–416

    Article  CAS  Google Scholar 

  22. Burge PS, Edge G, Hawkins R, White V, Newman Taylor AJ (1981) Occupational asthma in a factory making flux-cored solder containing colophony. Thorax 36:828–834

    Article  PubMed  CAS  Google Scholar 

  23. Carillo T, Blanco C, Quiralte J, Castillo R, Cuevas M, Rodriguez de Castro F (1995) Prevalence oflatex allergy among greenhouse workers. J Allergy Clin Immunol 96:699–701

    Article  Google Scholar 

  24. Chapman MD, Heymann PW, Sporik RB, Platts-Mills TAE (1995) Monitoring allergen exposure in asthma: new treatment strategies. Allergy 50: 29–33

    Article  PubMed  CAS  Google Scholar 

  25. Cremer R, Hoppe A, Korsch E, Kleine-Diepenbruck U, Bläker F (1997) Natural rubber latex allergy: prevalence and risk factors in patients with spina bifida compared with atopic children and controls. Europ J Ped, im Druck

    Google Scholar 

  26. Cullinan P, Lowson D, Nieuwenhuijsen MJ, Gordon S, Tee RD, Venables KM, McDonald JG, Newman Taylor AJ (1994) Work related symptoms, sensitisation, and estimated exposure in workers not previously exposed to laboratory rats. Occ Env Med 51: 589–592

    Article  CAS  Google Scholar 

  27. Custovic A, Green R, Taggart SCO, Smith A, Pickering CAC, Chapman MD, Woodcock A (1996) Domestic allergens in public places H:doc (Can fl) and cockroach (Bla g2) allergens in dust and mite, cat, dog and cockroach allergens in the air in public buildings. Clin Exp Allergy 26: 1246–1252

    Article  PubMed  CAS  Google Scholar 

  28. Custovic A, Taggart SCO, Francis HC, Chapman MD, Woodcock A (1996) Exposure to house dust mite allergens and the clinical activity of asthma. J Allergy Clin Immunol 98:64–72

    Article  PubMed  CAS  Google Scholar 

  29. Danne T, Niggemann B, Weber B, Wahn U (1997) Prevalence oflatex-specific IgE antibodies in atopic and nonatopic children with type I diabetes. Diabetes Care 20:476–478

    Article  PubMed  CAS  Google Scholar 

  30. Douglas RJ, Morton D, Czarny RE, O’Hehir (1997) Prevalence of 19B-mediated allergy to latex in hospital nursing staff. Aust N Z J Med 27: 165–169

    Article  PubMed  CAS  Google Scholar 

  31. Drexler H, Lehnert G (1996) Latexallergie - das geht uns alle an. Dtsch med Wschr 121: 1198–1203

    Article  PubMed  CAS  Google Scholar 

  32. Endres P, Müller-Querenheim J (1994) Alveolitiden, Granulomatosen. In: Ferlinz R (Hrsg) Pneumologie in Klinik und Praxis, Georg Thieme Verlag, Stuttgart - New York, 487–540

    Google Scholar 

  33. Fernandez-Caldas E (1997) Mite species of allergologic importance in Europe. Allergy 52:383–387

    Article  PubMed  CAS  Google Scholar 

  34. Gesundheitsgefährdung im Friseurhandwerk (1996) Tagungsbericht 8. In: Schriftenreihe der Bundesanstalt für Arbeitsmedizin, Berlin

    Google Scholar 

  35. Getreidemehlstäube Roggen/Weizen (1995) MAK 21

    Google Scholar 

  36. Glovsky MM, Miguel AG, Cass GR (1997) Particulate air pollution: possible relevance in asthma. Allergy Asthma Proc 18 (3): 163–166

    Article  PubMed  CAS  Google Scholar 

  37. Gordon S (1997) Occupational sensitization to laboratory animals. Clinical and Experimental Allergy 27: 603–605

    Article  PubMed  CAS  Google Scholar 

  38. Grzybowski M, Ownby DR, Peyser PA, Johnson CC, Schork MA (1996) The prevalence of anti -latex IgE antibodies among registered nurses. J Allergy Clin Immunol 98: 535–544

    Article  PubMed  CAS  Google Scholar 

  39. Heese A, Peters K-P, Koch HU, Hornstein OP (1994) Allergien gegen Latexhandschuhe. Gynäkologie 27:336–347

    CAS  Google Scholar 

  40. Henderson A, Englisch PN, Vecht RJ (1968) Pulmonary aspergiliosis: survey of its occurance in patients with chronic lung disease and discussion of the significance of diagnosis tests. Thorax 513–518

    Google Scholar 

  41. Hinze S, Bergman K-Ch, Løwenstein H, Nordskov Hansen G (1996) Differente Schwellenwertkonzentrationen flir Sensibilisierungen durch das Rinderhaarallergen Bos d2 bei atopischen und nichtatopischen Landwirten. Pneumologie 50: 177–181

    PubMed  CAS  Google Scholar 

  42. Hollander A, Run van P, Spithoven J, Heederik D, Doekes G (1997) Exposure of laboratory animal workers to airborne rat and mouse urine allergens. Clin Exp Allergy 27:617–626

    Article  PubMed  CAS  Google Scholar 

  43. Houba R, Heederik DJJ, Doekes G, van Run PEM (1996) Exposure-sensitization relationship for a-Amylase allergens in the baking industry. Am J Respir Crit Care Med 154: 130–136

    PubMed  CAS  Google Scholar 

  44. Huber H, Ammon J, Baur X (1997) Bronchialer Hyperreaktivitatstest (Kontraktionstest). In: Baur X (Hrsg) Lungenfunktionspriifung und Allergiediagnostik. Dustri-Verlag: MünchenDeisenhofen

    Google Scholar 

  45. Hunskaar S, Fosse RT (1990) Allergy to laboratory mice and rats: a review of the pathophysiology, epidemiology and clinical aspects. Lab Animals 24: 358–374

    Article  CAS  Google Scholar 

  46. Imaoka K, Miyazawa H, Nishihata S, Sakaguchi M, Inouye S (1996) Effect of pollen exposure on serum IgE and IgG antibody responses in japanese cedar pollinosis patients. Allergology Int 45: 159–162

    Article  Google Scholar 

  47. Jaeger D, Engelke T, Rennert S, Czuppon AB, Baur X (1993) Stufendiagnostik der respiratorischen Latexallergie. Pneumologie 474: 91–96

    Google Scholar 

  48. Jarvis D, Chinn S, Luczynska C, Burney P (1996) Association of respiratory symptoms and lung function in young adults with use of domestic gas appliances. The Lancet 347:426–431

    Article  CAS  Google Scholar 

  49. Jorde W (1996) Mastzellen - Allergenextrakte - Schimmelpilze und Enzyme als AllergeneN ahrungsmittelallergie - Alveolitis in Allergologie für die Praxis 4. Dustri -Verlag Dr. Karl Feistle, München-Deisenhofen

    Google Scholar 

  50. Karol MH (1983) Concentration-dependent immunologic response to toluene diisocyanate (TDI) following inhalation exposure. Toxicol Appl Pharmacol 68:229–241

    Article  PubMed  CAS  Google Scholar 

  51. Kelly KJ, Kurup V, Zacharisen M, Resnick A, Fink IN (1993) Skin and serologic testing in the diagnosis of latex allergy. J Allergy Clin Immunol 91: 1140–1145

    Article  PubMed  CAS  Google Scholar 

  52. Kelly KJ (1995) Management of the latex-allergic patient. Imm and All Clin of N Amer 15: 139–157

    Google Scholar 

  53. Kibby T, Akt M (1997) Prevalence of latex sensitization in a hospital employee population. Ann Allergy Asthma Immunol 78:41–44

    Article  PubMed  CAS  Google Scholar 

  54. Knox RB, Suphioglu C, Taylor P, Desal R, Watson HC, Peng JL, Bursil (1997) Major grass pollen allergen Lol p 1 binds to diesel exhaust particles: implications for asthma and air pollution. Clin Exp Allergy 27(3):246–251

    Article  PubMed  CAS  Google Scholar 

  55. Kongreßbericht (1994) Heuschnupfen - Neue Erkenntnisse zur Pathogenese, therapeutische Konsequenzen in Allergologie. Sonderdruck, Dustri Verlag, München -Deisenhofen

    Google Scholar 

  56. Konrad C, Fieber T, Gerber H, Schüpfer G, MülIner G (1997) The prevalence of latex sensitivity among anesthesiology staff. Anesth Analg 84: 629–633

    PubMed  CAS  Google Scholar 

  57. Kujala VM, Reijula ER (1995) Glove-induced dermal and respiratory symptoms among health care workers in one Finnish hospital. Am J of Ind Med 28: 89–98

    Article  CAS  Google Scholar 

  58. Lagier F, Vervloet D, Lhermet I, Poyen D, Charpin D (1992) Prevalence of latex allergy in operating room nurses. J Allergy Clin Immunol 90: 319–322

    Article  PubMed  CAS  Google Scholar 

  59. Lemière C, Cartier A, Dolovich J, Chan-Yeung M, Grammer L, Ghezzo H, L’Archeveque J, Malo JL (1996) Outcome of Specific Bronchial Responsiveness to Occupational Agents after Removal from Exposure. Am J Respir Crit Care Med 154:329–333

    PubMed  Google Scholar 

  60. Liebers V, Hoernstein M, Baur X (1993) Humoral immune response to the insect allergen Chi t 1 in aquarists and fish-food factory workers. Allergy 48: 236–239

    Article  PubMed  CAS  Google Scholar 

  61. Liebers V, v Kampen V, Sander I, Raulf-Heimsoth M, Rozynek P, Baur X (1995) Aktuelle Aspekte der Allergieforschung. MMV Medizin Verlag GmbH München. Allergo J 5; 4:280–288

    Google Scholar 

  62. Liebers V, van Kampen V, Baur X (1997) Dosis-Wirkungsbeziehungen bei arbeits- und umweltbedingten Atemwegsallergien. Arbeitsmed Sozialmed Umweltmed 32: 212–218

    Google Scholar 

  63. Liou SH, Yang JL, Cheng SY, Lai FM (1996) Respiratory symptoms and pulmonary function among wood dust -exposed joss stick workers. Int Arch Occup Environ Health, Springer Verlag, Berlin 68: 154–160

    CAS  Google Scholar 

  64. Liss GM, Bernstein D, Genesove L, Roos JO, Lim J (1993) Assessment of risk factors for IgEmediated sensitization to tetrachlorophthalic anhydride. J Allergy Clin Immunol 92 (2): 237–247

    Article  PubMed  CAS  Google Scholar 

  65. Menz G, Ismail C, Crameri R (1996) Die allergische bronchopulmonale Aspergillose. Georg Thieme Verlag, Stuttgart - New York. Pneumologie 50:419–427

    PubMed  CAS  Google Scholar 

  66. Miguel AG, Cass GR, Weiss J, Glovsky MM (1996) Latex allergens in tire dust and airborne particles. Environ Health Perspect 104 (11): 1180–1186

    Article  PubMed  CAS  Google Scholar 

  67. Moneret-Vautrin D, Beaudouin E, Widmer S, Mouton C, Kanny G, Prestat F, Kohler C, Feldmann L (1993) Prospective study of risk factors in natural rubber latex hypersensitivity. J Allergy Clin Immunol 92: 668–677

    Article  PubMed  CAS  Google Scholar 

  68. Newman Taylor AJ, Gordon S (1993) Laboratory animal and insect allergy. In: Bernstein IL, Chan-Yeung M, Malo IL, Bernstein DI (Eds): Asthma in the workplace. New York: Marcel Dekker, Inc, pp. 399–414

    Google Scholar 

  69. Noertjojo H, Dimich-Ward H, Peelen S, Dittrick M, Kennedy S, Chan-Yeung M (1996) Western Red cedar dust exposure and lung funktion: a dose-response relationship. Exposure and lung function: a dose-response relationship. Am J Resp Crit Care Med 154:968–973

    PubMed  CAS  Google Scholar 

  70. Orfan NA, Reed R, Dykewicz MS, Ganz M, Kolski GB (1994) Occupational asthma in a latex doll manufacturing plant. J Allergy Clin Immunol 94: 826–830

    Article  PubMed  CAS  Google Scholar 

  71. Pecquet C, Laynadier F, Dry J (1990) Contact urticaria and anaphylaxis to natural rubber. J Am Acad Dermatol 22: 631–633

    Article  PubMed  CAS  Google Scholar 

  72. Prieto JL, Guitièrrez V, Bertó JM, Camps B (1996) Sensivitity and maximal response to methacholine in perennial and seasonal allergic rhinitis. Clinical and Experimental Allergy 26:61–67

    Article  PubMed  CAS  Google Scholar 

  73. Renström A, Malmberg P, Larsson K, Larsson PH, Sundblad BM (1995) Allergic sensitization is associated with increased bronchial responsiveness: a prospective study of allergy to laboratory animals. Eur Respir J 8: 1514–1519

    PubMed  Google Scholar 

  74. Romieu I, Meneses F, Ruiz S, Sienra JJ, Huerta J, White MC, Etzel RA (1996) Effects of Air Pollution on the Respiratory Health of Asthmatic Children Living in Mexico City. Am J Respir Crit Care Med 154:300–307

    PubMed  CAS  Google Scholar 

  75. Rosenberg M, Patterson R, Mintzer P, Cooper B, Roberts M, Harris KE (1977) Clinical and immunological criteria for the diagnosis of allergic bronchopulmonary aspergillosis. Ann Intern Med 71: 115

    Google Scholar 

  76. Sakaguchi M, Inouye S, Sasaki R, Hashimoto M, Kobayashi C, Yasueda H (1995?) Measurement of airborne mite allergen exposure in individual subjects. J Allergy Clin Immunol 97; 5:1040–1044

    Google Scholar 

  77. Sander I, Bauer X, Isringhausen-Bley, Rozynek P (1993) Aspergillus Amylase als Bäckerallergen. Allergologie 16: 87–90

    CAS  Google Scholar 

  78. Sieber W, Siemon G (1996) Exogen-allergische Alveolitis durch Pilzsporen in schimmeliger Blumenerde. Allergologie 19; 3: 142–144

    Google Scholar 

  79. Slater JE (1994) Latex allergy. J Allergy Clin Immunol 94: 139–149

    PubMed  CAS  Google Scholar 

  80. Storm van’s Gravesand, Moseler M, Kuehr J (1996) The most common phenotypes of sensitization to inhalant allergens in childhood. Clinical and Experimental Allergy 27:646–652

    Google Scholar 

  81. Straube M, Szliska C, Schwanitz HJ (1996) Allergene und Irritanzen im Bäckerhandwerk. Allergologie 19:494–499

    Google Scholar 

  82. Sunyer J, Antó JM, Castellsagué J, Soriano JB, Roca J (1996) Spanish Group of the European Study of Asthma: Total serum IgE is associates with asthma independently of specific IgE levels. Eur Respir J 9: 1880–1884

    Article  Google Scholar 

  83. Swanson MC, Bubak ME; Hunt LW, Yunginger JW, Warner MA, Reed CE (1994) Quantification of occupational latex aero allergens in a medical center. J Allergy Clin Immunol 94:139–149

    Article  Google Scholar 

  84. Tarlo MS, Sussman G, Contala A, Swanson MC (1994) Control of airborne latex by use of powder free gloves. J Allergy Clin Immunol 93: 985–989

    Article  PubMed  CAS  Google Scholar 

  85. Tarlo SM, Wong L, Roos J, Booth N (1990) Occupational asthma caused by latex in a surgical glove manufacturing plant. J Allergy Clin Immunol 85: 626–631

    Article  PubMed  CAS  Google Scholar 

  86. Taylor Newman AJ (1996) Respiratory irritants encountered at work. In: Occupational lung disease. Thorax 51: 531–545

    Google Scholar 

  87. Thompson RN, Nau CA, Lawrence CH (1966) Identification of vehicle tire rubber in roadway dust. Am Ind Hyg Assoc J 27 (6):488–495

    Article  PubMed  CAS  Google Scholar 

  88. Turjanmaa K (1987) Incidence of immediate allergy to latex gloves in hospital personnel. Contact Dermatitis 17:270–275

    Article  PubMed  CAS  Google Scholar 

  89. Vandenplas O, Delwiche JP, Evrard G, Aimont P, van der Brempt X, Jamart J, Delaunois L (1995) Prevalence of occupational asthma due to latex among hospital personnel. Am J Respir Crit Care Med 151: 54–60

    PubMed  CAS  Google Scholar 

  90. Vanhanen M, Tuomi T, Hokkanen H, Tupasela O, Toumainen A, Holmberg PC, Leisola M, Nordmann H (1996) Enzyme exposure and enzyme sensitisation in the baking industry. Occupational and Environmental Medicine 53: 670–676

    Article  PubMed  CAS  Google Scholar 

  91. Wahn U, Lau S (1994) Die Bedeutung der Allergenexposition für die Entstehung allergischer Atemwegserkrankungen - speziell des,,Hausstaub-Asthmas“. Pneumologie 48: 89–90

    PubMed  CAS  Google Scholar 

  92. Wichmann HE (1996) Possible explanation for the different trends of asthma and allergy in east and west Germany. Clinical and Experimental Allergy 26: 621–623

    Article  PubMed  CAS  Google Scholar 

  93. Wütherich B, Schindler C, Leuenberger P, Ackermann-Liebrich U (1995) Prevalence of Atopy and Pollinosis in the Adult Population of Switzerland (SAPALDIA Study). Inter Arch Allergy Immunol 106: 149–156

    Article  Google Scholar 

  94. Yassin MS, Liertl MB, Fisher TJ, O’Brien K, Cross J, Steinmetz C (1994) Latex allergy in hospital employees. Ann Allergy 85: 626–631

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Allmers, H. (1998). Natürliche und künstliche Allergene. In: Schultz, K., Petro, W. (eds) Pneumologische Umweltmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72021-5_22

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-72021-5_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72022-2

  • Online ISBN: 978-3-642-72021-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics