Zusammenfassung
Der Anstieg von allergischen Erkrankungen im Bereich des Hautorganes und der Atemwege hat in den letzten Jahren zu vielen Spekulationen über die Gründe und Ursachen geführt. In diesem Kapitel sollen einige Gedanken und Hypothesen zur Pathogenese vorgestellt werden. Weiterhin solI hier auf Dosis-Wirkungsbeziehungen und inhalative Verursachung von Sensibilisierungen eingegangen werden. Abschließend sollen einige Umwelt- und Arbeitsbereiche exemplarisch vorgestellt werden.
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Literatur
Allmers H, Huber H, Baur X (1997) Bronchopulmonale Schimmelpilzallergie eines Müllwerkers. Arbeitsmed Sozialmed Umweltmed 32: 64–67
Allmers H, Kirov A, Hagemeyer O, Huber H, Walther JW, Baur X (1996) Latexsensibilisierung und Latexallergenkonzentration in der Luft. Ergebnis einer Querschnittsuntersuchung in einem Krankenhaus und in Arztpraxen. Allergologie 19: 68–70
Allmers H, Kirchner B, Huber H, Chen Z, Walther JW, Baur X (1996): Latenzzeit zwischen Exposition und Symptomen bei Allergie gegen Naturlatex. Dtsch med Wschr 121: 823–828
Alroth M, Alenius H, Turjanmaas K, Mäkinen-Kiljunen S, Reunala T, Palosuo T (1995) Cross-reacting allergens in natural rubber latex and avocado. J Allergy Clin Immunol 96:167–173
Antó JM, Sunyer J, Taylor Newman AJ (1996) Comparison of soybean epidemic asthma and occupational asthma in Occupational Lung Disease. Thorax 51:743–749
Arellano R, Bradley J, Sussman G (1992) Prevalence of latex sensitization among hospital physicians occupationally exposed to latex gloves. Anesthesiology 77: 905–908
Baur X, Allmers H (1996) Berufsbedingte Allergien. Diagnostisches Vorgehen in der Praxis. Praxismagazin med. 3/96 S. 30–35
Baur X, Hahn D, Weiss W (1988) Allergische bronchopulmonale Aspergillose mit heustaubinduzierter Alveolitis und Asthma bronchiale. Dtsch Med W schr 113: 1105
Baur X (1995) Wirkung von Isocyanaten und anderen niedermolekularen Substanzen auf die Atemwege und das Immunsystem. Atemw Lungenkrkh 4: 184–188
Baur X (1990) Inhalative Allergene und Irritantien am Arbeitsplatz. Allergologie 13; 4:134–139 Sonderdruck aus Allergologie, Dustri Verlag München-Deisenhofen
Bauer X und Mitglieder der interdisziplinären Arbeitsgruppe (1996) Naturlatex-AllergieEmpfehlungen der interdisziplinaren Arbeitsgruppe. Allergologie 19: 248–251
Baur X, Jäger D (1990) Airborne antigens from latex gloves. Lancet 335:912
Baur X, Ammon J, Chen Z, Beckmann U, Czuppon AB (1993) Health risk in hospitals through airborne latex allergens for patients presensitised to latex. Lancet 342: 1148 -1149
Baur X, Chen Z, Allrners H, Beckmann U, Walther JW (1996) Relevance oflatex aeroallergen for healthcare workers. Allergology International 20: 105–111
Berky ZT, Luciano WJ, James WD (1992) Latex glove allergy. A survey of the US Army Dental Corps. J Arner Med A 268: 2695–2697
Berufskrankheiten-Verordnung (BeKV) vom 8. Dezember 1976, Bundesgesetzblatt I, S. 3329 in der Fassung der Zweiten Verordnung zur Änderung der Berufskrankheiten-Verordnung vom 18. Dezember 1992. Bundesgesetzblatt I, S. 2343
BGA (Bundesgesundheitsamt, Institut für Sozialmedizin und Epidemiologie) (1994) Die Gesundheit der Deutschen. Ein Ost-West-Vergleich. Soz Epi Hefte 4
Blaski CA, Clapp WD, Thorne PS, Quinn TJ, Watt JL, Frees KL, Yagla SJ, Schwartz DA (1996) The Role of Atopy in Grain Dust-Induced Airway Disease. Am J Respir Crit Care Med 154:334–340
Bohadana AB, Massin N, Wild P, Berthiot G (1996) Airflow obstruction in chalkpowder and sugar workers. Arch Occup Environ Health, Springer Verlag, Berlin 68: 243–248
Bolm Audorff U, Bienfait HG, Albracht G (1996) Staubexposition in Backerbetrieben. Zbl Arbeitsmed 46: 105–110
Brauer M, Kennedy SM (1996) Gas stoves and respiratory health. The Lancet 347:412–416
Burge PS, Edge G, Hawkins R, White V, Newman Taylor AJ (1981) Occupational asthma in a factory making flux-cored solder containing colophony. Thorax 36:828–834
Carillo T, Blanco C, Quiralte J, Castillo R, Cuevas M, Rodriguez de Castro F (1995) Prevalence oflatex allergy among greenhouse workers. J Allergy Clin Immunol 96:699–701
Chapman MD, Heymann PW, Sporik RB, Platts-Mills TAE (1995) Monitoring allergen exposure in asthma: new treatment strategies. Allergy 50: 29–33
Cremer R, Hoppe A, Korsch E, Kleine-Diepenbruck U, Bläker F (1997) Natural rubber latex allergy: prevalence and risk factors in patients with spina bifida compared with atopic children and controls. Europ J Ped, im Druck
Cullinan P, Lowson D, Nieuwenhuijsen MJ, Gordon S, Tee RD, Venables KM, McDonald JG, Newman Taylor AJ (1994) Work related symptoms, sensitisation, and estimated exposure in workers not previously exposed to laboratory rats. Occ Env Med 51: 589–592
Custovic A, Green R, Taggart SCO, Smith A, Pickering CAC, Chapman MD, Woodcock A (1996) Domestic allergens in public places H:doc (Can fl) and cockroach (Bla g2) allergens in dust and mite, cat, dog and cockroach allergens in the air in public buildings. Clin Exp Allergy 26: 1246–1252
Custovic A, Taggart SCO, Francis HC, Chapman MD, Woodcock A (1996) Exposure to house dust mite allergens and the clinical activity of asthma. J Allergy Clin Immunol 98:64–72
Danne T, Niggemann B, Weber B, Wahn U (1997) Prevalence oflatex-specific IgE antibodies in atopic and nonatopic children with type I diabetes. Diabetes Care 20:476–478
Douglas RJ, Morton D, Czarny RE, O’Hehir (1997) Prevalence of 19B-mediated allergy to latex in hospital nursing staff. Aust N Z J Med 27: 165–169
Drexler H, Lehnert G (1996) Latexallergie - das geht uns alle an. Dtsch med Wschr 121: 1198–1203
Endres P, Müller-Querenheim J (1994) Alveolitiden, Granulomatosen. In: Ferlinz R (Hrsg) Pneumologie in Klinik und Praxis, Georg Thieme Verlag, Stuttgart - New York, 487–540
Fernandez-Caldas E (1997) Mite species of allergologic importance in Europe. Allergy 52:383–387
Gesundheitsgefährdung im Friseurhandwerk (1996) Tagungsbericht 8. In: Schriftenreihe der Bundesanstalt für Arbeitsmedizin, Berlin
Getreidemehlstäube Roggen/Weizen (1995) MAK 21
Glovsky MM, Miguel AG, Cass GR (1997) Particulate air pollution: possible relevance in asthma. Allergy Asthma Proc 18 (3): 163–166
Gordon S (1997) Occupational sensitization to laboratory animals. Clinical and Experimental Allergy 27: 603–605
Grzybowski M, Ownby DR, Peyser PA, Johnson CC, Schork MA (1996) The prevalence of anti -latex IgE antibodies among registered nurses. J Allergy Clin Immunol 98: 535–544
Heese A, Peters K-P, Koch HU, Hornstein OP (1994) Allergien gegen Latexhandschuhe. Gynäkologie 27:336–347
Henderson A, Englisch PN, Vecht RJ (1968) Pulmonary aspergiliosis: survey of its occurance in patients with chronic lung disease and discussion of the significance of diagnosis tests. Thorax 513–518
Hinze S, Bergman K-Ch, Løwenstein H, Nordskov Hansen G (1996) Differente Schwellenwertkonzentrationen flir Sensibilisierungen durch das Rinderhaarallergen Bos d2 bei atopischen und nichtatopischen Landwirten. Pneumologie 50: 177–181
Hollander A, Run van P, Spithoven J, Heederik D, Doekes G (1997) Exposure of laboratory animal workers to airborne rat and mouse urine allergens. Clin Exp Allergy 27:617–626
Houba R, Heederik DJJ, Doekes G, van Run PEM (1996) Exposure-sensitization relationship for a-Amylase allergens in the baking industry. Am J Respir Crit Care Med 154: 130–136
Huber H, Ammon J, Baur X (1997) Bronchialer Hyperreaktivitatstest (Kontraktionstest). In: Baur X (Hrsg) Lungenfunktionspriifung und Allergiediagnostik. Dustri-Verlag: MünchenDeisenhofen
Hunskaar S, Fosse RT (1990) Allergy to laboratory mice and rats: a review of the pathophysiology, epidemiology and clinical aspects. Lab Animals 24: 358–374
Imaoka K, Miyazawa H, Nishihata S, Sakaguchi M, Inouye S (1996) Effect of pollen exposure on serum IgE and IgG antibody responses in japanese cedar pollinosis patients. Allergology Int 45: 159–162
Jaeger D, Engelke T, Rennert S, Czuppon AB, Baur X (1993) Stufendiagnostik der respiratorischen Latexallergie. Pneumologie 474: 91–96
Jarvis D, Chinn S, Luczynska C, Burney P (1996) Association of respiratory symptoms and lung function in young adults with use of domestic gas appliances. The Lancet 347:426–431
Jorde W (1996) Mastzellen - Allergenextrakte - Schimmelpilze und Enzyme als AllergeneN ahrungsmittelallergie - Alveolitis in Allergologie für die Praxis 4. Dustri -Verlag Dr. Karl Feistle, München-Deisenhofen
Karol MH (1983) Concentration-dependent immunologic response to toluene diisocyanate (TDI) following inhalation exposure. Toxicol Appl Pharmacol 68:229–241
Kelly KJ, Kurup V, Zacharisen M, Resnick A, Fink IN (1993) Skin and serologic testing in the diagnosis of latex allergy. J Allergy Clin Immunol 91: 1140–1145
Kelly KJ (1995) Management of the latex-allergic patient. Imm and All Clin of N Amer 15: 139–157
Kibby T, Akt M (1997) Prevalence of latex sensitization in a hospital employee population. Ann Allergy Asthma Immunol 78:41–44
Knox RB, Suphioglu C, Taylor P, Desal R, Watson HC, Peng JL, Bursil (1997) Major grass pollen allergen Lol p 1 binds to diesel exhaust particles: implications for asthma and air pollution. Clin Exp Allergy 27(3):246–251
Kongreßbericht (1994) Heuschnupfen - Neue Erkenntnisse zur Pathogenese, therapeutische Konsequenzen in Allergologie. Sonderdruck, Dustri Verlag, München -Deisenhofen
Konrad C, Fieber T, Gerber H, Schüpfer G, MülIner G (1997) The prevalence of latex sensitivity among anesthesiology staff. Anesth Analg 84: 629–633
Kujala VM, Reijula ER (1995) Glove-induced dermal and respiratory symptoms among health care workers in one Finnish hospital. Am J of Ind Med 28: 89–98
Lagier F, Vervloet D, Lhermet I, Poyen D, Charpin D (1992) Prevalence of latex allergy in operating room nurses. J Allergy Clin Immunol 90: 319–322
Lemière C, Cartier A, Dolovich J, Chan-Yeung M, Grammer L, Ghezzo H, L’Archeveque J, Malo JL (1996) Outcome of Specific Bronchial Responsiveness to Occupational Agents after Removal from Exposure. Am J Respir Crit Care Med 154:329–333
Liebers V, Hoernstein M, Baur X (1993) Humoral immune response to the insect allergen Chi t 1 in aquarists and fish-food factory workers. Allergy 48: 236–239
Liebers V, v Kampen V, Sander I, Raulf-Heimsoth M, Rozynek P, Baur X (1995) Aktuelle Aspekte der Allergieforschung. MMV Medizin Verlag GmbH München. Allergo J 5; 4:280–288
Liebers V, van Kampen V, Baur X (1997) Dosis-Wirkungsbeziehungen bei arbeits- und umweltbedingten Atemwegsallergien. Arbeitsmed Sozialmed Umweltmed 32: 212–218
Liou SH, Yang JL, Cheng SY, Lai FM (1996) Respiratory symptoms and pulmonary function among wood dust -exposed joss stick workers. Int Arch Occup Environ Health, Springer Verlag, Berlin 68: 154–160
Liss GM, Bernstein D, Genesove L, Roos JO, Lim J (1993) Assessment of risk factors for IgEmediated sensitization to tetrachlorophthalic anhydride. J Allergy Clin Immunol 92 (2): 237–247
Menz G, Ismail C, Crameri R (1996) Die allergische bronchopulmonale Aspergillose. Georg Thieme Verlag, Stuttgart - New York. Pneumologie 50:419–427
Miguel AG, Cass GR, Weiss J, Glovsky MM (1996) Latex allergens in tire dust and airborne particles. Environ Health Perspect 104 (11): 1180–1186
Moneret-Vautrin D, Beaudouin E, Widmer S, Mouton C, Kanny G, Prestat F, Kohler C, Feldmann L (1993) Prospective study of risk factors in natural rubber latex hypersensitivity. J Allergy Clin Immunol 92: 668–677
Newman Taylor AJ, Gordon S (1993) Laboratory animal and insect allergy. In: Bernstein IL, Chan-Yeung M, Malo IL, Bernstein DI (Eds): Asthma in the workplace. New York: Marcel Dekker, Inc, pp. 399–414
Noertjojo H, Dimich-Ward H, Peelen S, Dittrick M, Kennedy S, Chan-Yeung M (1996) Western Red cedar dust exposure and lung funktion: a dose-response relationship. Exposure and lung function: a dose-response relationship. Am J Resp Crit Care Med 154:968–973
Orfan NA, Reed R, Dykewicz MS, Ganz M, Kolski GB (1994) Occupational asthma in a latex doll manufacturing plant. J Allergy Clin Immunol 94: 826–830
Pecquet C, Laynadier F, Dry J (1990) Contact urticaria and anaphylaxis to natural rubber. J Am Acad Dermatol 22: 631–633
Prieto JL, Guitièrrez V, Bertó JM, Camps B (1996) Sensivitity and maximal response to methacholine in perennial and seasonal allergic rhinitis. Clinical and Experimental Allergy 26:61–67
Renström A, Malmberg P, Larsson K, Larsson PH, Sundblad BM (1995) Allergic sensitization is associated with increased bronchial responsiveness: a prospective study of allergy to laboratory animals. Eur Respir J 8: 1514–1519
Romieu I, Meneses F, Ruiz S, Sienra JJ, Huerta J, White MC, Etzel RA (1996) Effects of Air Pollution on the Respiratory Health of Asthmatic Children Living in Mexico City. Am J Respir Crit Care Med 154:300–307
Rosenberg M, Patterson R, Mintzer P, Cooper B, Roberts M, Harris KE (1977) Clinical and immunological criteria for the diagnosis of allergic bronchopulmonary aspergillosis. Ann Intern Med 71: 115
Sakaguchi M, Inouye S, Sasaki R, Hashimoto M, Kobayashi C, Yasueda H (1995?) Measurement of airborne mite allergen exposure in individual subjects. J Allergy Clin Immunol 97; 5:1040–1044
Sander I, Bauer X, Isringhausen-Bley, Rozynek P (1993) Aspergillus Amylase als Bäckerallergen. Allergologie 16: 87–90
Sieber W, Siemon G (1996) Exogen-allergische Alveolitis durch Pilzsporen in schimmeliger Blumenerde. Allergologie 19; 3: 142–144
Slater JE (1994) Latex allergy. J Allergy Clin Immunol 94: 139–149
Storm van’s Gravesand, Moseler M, Kuehr J (1996) The most common phenotypes of sensitization to inhalant allergens in childhood. Clinical and Experimental Allergy 27:646–652
Straube M, Szliska C, Schwanitz HJ (1996) Allergene und Irritanzen im Bäckerhandwerk. Allergologie 19:494–499
Sunyer J, Antó JM, Castellsagué J, Soriano JB, Roca J (1996) Spanish Group of the European Study of Asthma: Total serum IgE is associates with asthma independently of specific IgE levels. Eur Respir J 9: 1880–1884
Swanson MC, Bubak ME; Hunt LW, Yunginger JW, Warner MA, Reed CE (1994) Quantification of occupational latex aero allergens in a medical center. J Allergy Clin Immunol 94:139–149
Tarlo MS, Sussman G, Contala A, Swanson MC (1994) Control of airborne latex by use of powder free gloves. J Allergy Clin Immunol 93: 985–989
Tarlo SM, Wong L, Roos J, Booth N (1990) Occupational asthma caused by latex in a surgical glove manufacturing plant. J Allergy Clin Immunol 85: 626–631
Taylor Newman AJ (1996) Respiratory irritants encountered at work. In: Occupational lung disease. Thorax 51: 531–545
Thompson RN, Nau CA, Lawrence CH (1966) Identification of vehicle tire rubber in roadway dust. Am Ind Hyg Assoc J 27 (6):488–495
Turjanmaa K (1987) Incidence of immediate allergy to latex gloves in hospital personnel. Contact Dermatitis 17:270–275
Vandenplas O, Delwiche JP, Evrard G, Aimont P, van der Brempt X, Jamart J, Delaunois L (1995) Prevalence of occupational asthma due to latex among hospital personnel. Am J Respir Crit Care Med 151: 54–60
Vanhanen M, Tuomi T, Hokkanen H, Tupasela O, Toumainen A, Holmberg PC, Leisola M, Nordmann H (1996) Enzyme exposure and enzyme sensitisation in the baking industry. Occupational and Environmental Medicine 53: 670–676
Wahn U, Lau S (1994) Die Bedeutung der Allergenexposition für die Entstehung allergischer Atemwegserkrankungen - speziell des,,Hausstaub-Asthmas“. Pneumologie 48: 89–90
Wichmann HE (1996) Possible explanation for the different trends of asthma and allergy in east and west Germany. Clinical and Experimental Allergy 26: 621–623
Wütherich B, Schindler C, Leuenberger P, Ackermann-Liebrich U (1995) Prevalence of Atopy and Pollinosis in the Adult Population of Switzerland (SAPALDIA Study). Inter Arch Allergy Immunol 106: 149–156
Yassin MS, Liertl MB, Fisher TJ, O’Brien K, Cross J, Steinmetz C (1994) Latex allergy in hospital employees. Ann Allergy 85: 626–631
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Allmers, H. (1998). Natürliche und künstliche Allergene. In: Schultz, K., Petro, W. (eds) Pneumologische Umweltmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72021-5_22
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