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Treatment of Ph+ and t(4;11)+ Acute Lymphoblastic Leukemia in Adults

  • Conference paper
Acute Leukemias VII

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 39))

Abstract

About 20–25% of adult patients with acute lymphoblastic leukemia (ALL) present with a Philadelphia chromosome t(9;22) as cytogenetic marker and/or on a molecular level with the corresponding BCR-ABLrearrangement [1–4]. The proportion of ALL-patients with Ph+/BCR-ABL+ ALL increases with age. The median age of patients with BCR-ABL+ ALL in the German multicenter adult ALL (GMALL) trials is 45 years [4].

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Author information

Authors and Affiliations

  1. Medizinische Klinik III, Klinikum der Johann Wolfgang Goethe Universität Frankfurt, Frankfurt, Germany

    H. Martin, N. Goekburget, J. Atta & D. Hoelzer

  2. Robert Rössle-Klinik, UK Rudolf Virchow, Berlin, Germany

    W.-D. Ludwig

Authors
  1. H. Martin
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  2. N. Goekburget
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  3. J. Atta
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  4. W.-D. Ludwig
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  5. D. Hoelzer
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Editor information

Editors and Affiliations

  1. Department of Internal Medicine, University of Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany

    W. Hiddemann  & B. Wörmann  & 

  2. Department of Internal Medicine, USA

    T. Büchner

  3. Department of Pediatrics, University of Münster, Albert-Schweitzer-Straße 33, 48149, Münster, Germany

    J. Ritter  & U. Creutzig  & 

  4. Dept. of Hematology, University of Texas, Anderson Cancer Center, 1515 Holcombe Boulevard, 77030, Houston, Tx., USA

    M. Keating MD PhD  & W. Plunkett MD PhD  & 

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© 1998 Springer-Verlag Berlin Heidelberg

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Martin, H., Goekburget, N., Atta, J., Ludwig, WD., Hoelzer, D. (1998). Treatment of Ph+ and t(4;11)+ Acute Lymphoblastic Leukemia in Adults. In: Hiddemann, W., et al. Acute Leukemias VII. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 39. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71960-8_103

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  • DOI: https://doi.org/10.1007/978-3-642-71960-8_103

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71962-2

  • Online ISBN: 978-3-642-71960-8

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