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Effect of Gangliosides on Nerve Conduction Velocity During Diabetic Neuropathy in the Rat

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Gangliosides and Modulation of Neuronal Functions

Part of the book series: NATO ASI Series ((ASIH,volume 7))

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Abstract

Gangliosides, a class of glycosphingolipids, originally isolated from brain matter and described as substance X by Klenk (1), have been analyzed in detail since then and related to a number of biological functions (for review see 2,3). Among these functions a possible positive effect on neuronal degeneration has been proposed by several authors (4,5) and requires further evaluation with respect to the therapeutical potential of gangliosides in the course of neuropathies.

Dr. Madaus & Co., 5000 Cologne, FRG

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References

  1. Klenk E (1939) Beiträge zur Chemie der Lipoidosen. Niemann-Picksche Krankheit und amaurotische Idiotie. Hoppe-Seylers Z Physiol Chem 262: 128–143

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Author information

Authors and Affiliations

  1. Pro Science Private Research Institute GmbH, Am Pfad 8, D-6307, Linden 2, Federal Republic of Germany

    W. Dimpfel, M. Spüler & H.-U. Tüllner

Authors
  1. W. Dimpfel
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  2. M. Spüler
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  3. H.-U. Tüllner
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Editor information

Editors and Affiliations

  1. Zoological Institute, University of Stuttgart-Hohenheim, Garbenstr. 30, 7000, Stuttgart 70, Germany

    Hinrich Rahmann

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© 1987 Springer-Verlag Berlin Heidelberg

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Dimpfel, W., Spüler, M., Tüllner, HU. (1987). Effect of Gangliosides on Nerve Conduction Velocity During Diabetic Neuropathy in the Rat. In: Rahmann, H. (eds) Gangliosides and Modulation of Neuronal Functions. NATO ASI Series, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71932-5_58

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  • DOI: https://doi.org/10.1007/978-3-642-71932-5_58

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71934-9

  • Online ISBN: 978-3-642-71932-5

  • eBook Packages: Springer Book Archive

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