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Substrate Specifity of GM2 Synthase and GD3 Synthase of Golgi Vesicles Derived from Rat Liver

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Book cover Gangliosides and Modulation of Neuronal Functions

Part of the book series: NATO ASI Series ((ASIH,volume 7))

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Abstract

Several GM3 derivatives were synthesized which can be classified as follows: Lyso-G M3 derivatives with variation in the chain length of the fatty acid of the ceramide residue. NeuNH-G M3 derivatives which are modified at the 5-amino group of the neuraminic acid residue. G M3 -COOH derivatives altered at the carboxyl group of the neuraminic acid with concomitant loss of the negative charge. The structures of all these ganglioside derivatives were assured by FAB mass spectrometry.

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© 1987 Springer-Verlag Berlin Heidelberg

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Klein, D., Pohlentz, G., Schwarzmann, G., Sandhoff, K. (1987). Substrate Specifity of GM2 Synthase and GD3 Synthase of Golgi Vesicles Derived from Rat Liver. In: Rahmann, H. (eds) Gangliosides and Modulation of Neuronal Functions. NATO ASI Series, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71932-5_26

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  • DOI: https://doi.org/10.1007/978-3-642-71932-5_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71934-9

  • Online ISBN: 978-3-642-71932-5

  • eBook Packages: Springer Book Archive

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