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Mesenchymal-Epithelial Interactions in Neural Development pp 101–110Cite as

Cell Interactions During Kidney Development

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Part of the book series: NATO ASI Series ((ASIH,volume 5))

Abstract

Interactions between different tissue compartments are crucial for embryonic development. These interactions include long-range effects by serum factors (hormonese and growth factors), adhesive interactions between cells, and inductive interactions between two dissimilar cell populations located in close proximity to each other. In vitro cultures of embryonic tissues are well suited for analysis of these phenomena. In such cultures, the normal histoarchitecture is retained, but it is nevertheless possible to manipulate morphogenesis at least to some extent. Organ culture of embryonic tissues has been used to study the development of most parenchymal organs, such as the lung, heart, liver, many different glands, and the kidney. These studies have convincingly demonstrated the role of inductive interactions in development (see Wessells, 1977). We are using the developing kidney to study these phenomena.

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Author information

Authors and Affiliations

  1. Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft, Tübingen, West Germany

    P. Ekblom, E. Aufderheide, G. Klein, A. Kurz & A. Weller

Authors
  1. P. Ekblom
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  2. E. Aufderheide
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  3. G. Klein
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  4. A. Kurz
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  5. A. Weller
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Editor information

Editors and Affiliations

  1. Berlin Institute for Advanced Study, Zentrum Anatomie, Kreuzbergring 36, 3400, Göttingen, Germany

    Joachim R. Wolff

  2. Universität Göttingen, Zentrum Anatomie, Kreuzbergring 36, 3400, Göttingen, Germany

    Joachim R. Wolff

  3. Anatomiches Institut, Universität Kiel, Olshausentr. 40-60, Haus N10, 2300, Kiel, Germany

    Jobst Sievers

  4. Department of Anatomy, Guy’s Hospital Medical School, London, SE1 9RT, England

    Martin Berry

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© 1987 Springer-Verlag Berlin Heidelberg

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Ekblom, P., Aufderheide, E., Klein, G., Kurz, A., Weller, A. (1987). Cell Interactions During Kidney Development. In: Wolff, J.R., Sievers, J., Berry, M. (eds) Mesenchymal-Epithelial Interactions in Neural Development. NATO ASI Series, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71837-3_8

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  • DOI: https://doi.org/10.1007/978-3-642-71837-3_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71839-7

  • Online ISBN: 978-3-642-71837-3

  • eBook Packages: Springer Book Archive

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