Dubreuilh’s Melanosis

  • Julien Glicenstein
  • Jacques Ohana
  • Caroline Leclercq


This condition is also known by the name of senile lentigo, circumscribed precancerous melanosis, melanotic freckle (Hutchinson), lentigo maligna, etc. Dubreuilh’s circumscribed, precancerous melanosis is a noncongenital naevoid patch appearing after middle life and particularly affecting the face, more rarely the hands and legs. The importance of its study relates to its frequency and the major risk of transformation into malignant melanoma.


Marked Cell Proliferation Melanocytic Tumor Phalangeal Joint Nail Matrix Solar Keratose 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Andrade R (1972) Lentigo maligna (Hutchinson’s freckle). In: Demis JD, Crounse RG, Dobson RL, Mc Guires (eds) Clinical dermatology, vol 2, unit 11–54. Harper and Row, New YorkGoogle Scholar
  2. Andrade R (1976) Circumscribed precancerous melanosis (Dubreuilh). In: Andrade R, Gumport SL, Popkin GL, Rees TD (eds) Cancer of the skin. Saunders, Philadelphia, pp 679–702Google Scholar
  3. Clark WH Jr, Mihm MC Jr (1969) Lentigo maligna and lentigo maligna melanoma. Am J Pathol 55: 39PubMedGoogle Scholar
  4. Dubreuilh MW (1912) De la mélanose circonscrite précancéreuse. Ann Dermatol Syphiligr (Paris) 3: 129Google Scholar
  5. Hutchinson J (1892) On senile moles and senile freckles and on their relationship to cancerous processes. Arch Surg 2: 218Google Scholar
  6. Lupulescu A, Pinkus H, Birmingham DJ, Windekhe H, Posch JL (1973) Lentigo maligna of the fingertip–Clinical histologic and ultrastructural studies of two cases. Arch Dermatol 107: 717PubMedCrossRefGoogle Scholar
  7. Pinkus H, Mishima Y (1963) Benign and precancerous nonnevoid melanocytic tumors. Ann NY Acad Sci 100: 256Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Julien Glicenstein
    • 1
  • Jacques Ohana
    • 2
  • Caroline Leclercq
    • 3
  1. 1.ParisFrance
  2. 2.ParisFrance
  3. 3.ParisFrance

Personalised recommendations