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Radioimmunoassay in Basic and Clinical Pharmacology pp 315–350Cite as

Radioimmunoassay of Gastrointestinal Polypeptides

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 82))

Abstract

The gastrointestinal hormones comprise a group of peptides produced by endocrine cells that line the stomach and intestine. The pancreatic hormones insulin, glucagon, and pancreatic polypeptide are often included in this category. Several other peptides are produced in the gut exclusively by nerves or by both nerves and endocrine-type cells. These endocrine peptides and neuropeptides exert a wide variety of biologic effects on target organs in the gastrointestinal tract. They serve as endocrine and/or neurocrine regulators of many physiologic functions. They also produce clinical disease, most dramatically when there is massive overproduction by a hormone-secreting tumor.

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Authors
  1. J. H. Walsh
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  2. H. C. Wong
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Editors and Affiliations

  1. Institute of Pharmacology, Catholic University of the Sacred Heart, Largo Francesco Vito, 1, I-00168, Rome, Italy

    Carlo Patrono (Professor of Molecular Pharmacology) (Professor of Molecular Pharmacology)

  2. Institute of Pharmacology and Toxicology, Ruhr-University Bochum Im Lottental, P.O. Box 102148, D-4630, Bochum 1, Germany

    Bernhard A. Peskar (Professor of Pharmacology and Toxicology) (Professor of Pharmacology and Toxicology)

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Walsh, J.H., Wong, H.C. (1987). Radioimmunoassay of Gastrointestinal Polypeptides. In: Patrono, C., Peskar, B.A. (eds) Radioimmunoassay in Basic and Clinical Pharmacology. Handbook of Experimental Pharmacology, vol 82. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71809-0_13

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  • DOI: https://doi.org/10.1007/978-3-642-71809-0_13

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