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Drug Effects on Plasma Membrane Calcium Transport

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Calcium in Drug Actions

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 83))

Abstract

In this chapter we have concentrated mainly on the question of the effects of drugs on the plasma membrane Ca2+ pump. This is not an exhaustive review. We have reviewed mainly the literature files in our laboratory, concentrating on papers published in 1983, 1984, and 1985. There are a number of reviews in related areas, including calmodulin (CaM) (Tomlinson et al. 1984) and its drug interaction (Vincenzi 1981; Weiss et al. 1985; Roufogalis et al. 1983; Roufogalis 1985), regulation of calcium in cells (Carafoli 1985), the effects of drugs on membrane fluidity (Goldstein 1984), and reviews on plasma membrane (PM) Ca2+ pump ATPase (Itano and Penniston 1985) and Ca2+ transport (Carafoli 1984 a, b, c, d, 1985; Schatzmann 1983, 1985). Because relatively more is known about the Ca2+ pump in human red blood cells (RBCs) than in other types and species of cells, most of our concern has been with this type of cell. Ca2+ transport in the heart has been reviewed by Langer (1984) and Carafoli (1985).

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Authors
  1. F. F. Vincenzi
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  2. T. R. Hinds
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Editors and Affiliations

  1. Department of Physiology King’s College, University of London, Strand, London, WC2R 2LS, Great Britain

    Peter F. Baker (Professor Sc. D., F.R.S.) (Professor Sc. D., F.R.S.)

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Vincenzi, F.F., Hinds, T.R. (1988). Drug Effects on Plasma Membrane Calcium Transport. In: Baker, P.F. (eds) Calcium in Drug Actions. Handbook of Experimental Pharmacology, vol 83. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71806-9_8

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  • DOI: https://doi.org/10.1007/978-3-642-71806-9_8

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