Abstract
The bisphosphonates are a new class of drugs which have been developed in the past two decades for use in various diseases of bone, tooth, and calcium metabolism. Three are on the market today, while others are under clinical or preclinical investigation. This chapter will cover chemical and experimental aspects as well as clinical applications of these compounds. Literature is essentially limited to one reference, usually the original report. For two recent reviews, weighted somewhat differently and with more extensive references, see Fleisch (1983) and Francis and Martodam (1983).
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References
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Fleisch, H. (1988). Bisphosphonates: A New Class of Drugs in Diseases of Bone and Calcium Metabolism. In: Baker, P.F. (eds) Calcium in Drug Actions. Handbook of Experimental Pharmacology, vol 83. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71806-9_21
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