The Effect of Pentoxifylline on Cortical pO2 in Cat and Human Brain

  • R. Schultheiss
  • R. Leuwer
  • M. Hufnagel
  • E. Leniger-Follert
  • R. Wüllenweber
Conference paper
Part of the Advances in Neurosurgery book series (NEURO, volume 15)

Abstract

The effect of pentoxifylline (Trental) on cortical pO2 of normal cats was studied experimentally. Analogous measurements were performed in patients who underwent surgery for cerebrovascular disease.

Keywords

Respiration Neurol Nite Hema Pentoxifylline 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Beyreder J (1983) Use of pentoxifylline in the treatment of acute cerebrovascular insufficiency. Eur Neurol (Suppl. 1) 22:116–123PubMedCrossRefGoogle Scholar
  2. 2.
    Ehrly AM (1975) Beeinflussung der Verformbarkeit der Erythrocyten durch Pentoxifyllin. Med Welt 26:2300–2301PubMedGoogle Scholar
  3. 3.
    Hartmann A (1983) Effect of pentoxifylline on regional cerebral blood flow in patients with cerebral vascular disorders. Eur Neurol (Suppl 1) 22:108–115PubMedCrossRefGoogle Scholar
  4. 4.
    Hauss JK, Schönleben K, Spiegel HU (1982) Therapiekontrolle durch Überwachung des Gewebe-PO2. Eine tierexperimentelle und klinische Studie. In: Aktuelle Probleme in der Angiologie, Bd. 41. Huber, Bern Stuttgart WienGoogle Scholar
  5. 5.
    Hauss J, Schönleben K, Spiegel HU, Kessler M (1978) Measurements of local oxygen pressure in skeletal muscle of patients suffering from disturbances of arterial circulation. In: Silver IA, Erecinska M, Bicher HI (eds) Oxygen transport to tissue — III. Plenum Press, pp 419–422Google Scholar
  6. 6.
    Kessler M, Luebbers DW (1966) Aufbau und Anwendungsmöglichkeiten verschiedener pO2-Elektroden. Pflüg Arch 291:82Google Scholar
  7. 7.
    Luebbers DW (1977) Die Bedeutung des lokalen Gewebesauerstoffdruck-es und des pO2-Histogrammes für die Beurteilung der Sauerstoffversorgung eines Organs. Prakt Anästh 12:184–193Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • R. Schultheiss
    • 1
  • R. Leuwer
    • 1
  • M. Hufnagel
    • 1
  • E. Leniger-Follert
    • 1
  • R. Wüllenweber
    • 1
  1. 1.Neurochirurgische UniversitätsklinikBonn 1Germany

Personalised recommendations