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Blood Cells, Rheology, and Aging pp 127–138Cite as

Regulation of the Immune and Nonimmune Aging Process by the Major Histocompatibility Complex

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Abstract

Each species displays a characteristic maximum life span which is genetically determined and more or less independent of environmental influences, so long as the population size is large enough; for example, in man about 110 years, in the chimpanzee 55 years, and in mice 3½ years. By contrast, the average life span or “life expectancy” is influenced at least as much by environment, lifestyle, or health habits as by genetic endowment. These actuarial distinctions are important in understanding aging as a biologic phenomenon reflected in survival patterns.

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Authors
  1. R. L. Walford
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Editors and Affiliations

  1. Instituts für Gerontologie, Universität Erlangen-Nürnberg, Flurstraße 17, D-8500, Nürnberg, Germany

    Dieter Platt (Direktor) (Direktor)

  2. 2. Medizinischen Klinik, Klinikum Nürnberg, Flurstraße 17, D-8500, Nürnberg, Germany

    Dieter Platt (Direktor) (Direktor)

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© 1988 Springer-Verlag Berlin Heidelberg

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Walford, R.L. (1988). Regulation of the Immune and Nonimmune Aging Process by the Major Histocompatibility Complex. In: Platt, D. (eds) Blood Cells, Rheology, and Aging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71790-1_13

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  • DOI: https://doi.org/10.1007/978-3-642-71790-1_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71792-5

  • Online ISBN: 978-3-642-71790-1

  • eBook Packages: Springer Book Archive

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