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Regulation of the Immune and Nonimmune Aging Process by the Major Histocompatibility Complex

  • R. L. Walford
Conference paper

Abstract

Each species displays a characteristic maximum life span which is genetically determined and more or less independent of environmental influences, so long as the population size is large enough; for example, in man about 110 years, in the chimpanzee 55 years, and in mice 3½ years. By contrast, the average life span or “life expectancy” is influenced at least as much by environment, lifestyle, or health habits as by genetic endowment. These actuarial distinctions are important in understanding aging as a biologic phenomenon reflected in survival patterns.

Keywords

Major Histocompatibility Complex Xeroderma Pigmentosum Congenic Mouse Mixed Function Oxidase Maximum Life Span 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • R. L. Walford

There are no affiliations available

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