Hemodilution in Cerebral Infarction
Although experimental research on the cerebral circulation has now been intensively concerned for more than three decades with the pathogenesis of cerebral blood flow disorders and with cerebral infarction and its therapy, treatment of cerebral infarction continues to be one of the major problems of medicine. Vasodilatory substances, measures to raise blood pressure, hyperventilation, hyperbaric oxygen therapy, and finally thrombocyte aggregation inhibitors and calcium antagonists have all proved ineffective. There is the continuing great hope that patients with acute cerebral infarction can be effectively helped by means of correctly applied hemodilution therapy. Although this chapter has not yet been finally concluded, numerous research groups have now demonstrated the efficiency of hemodilution in the cerebral circulation, i.e., a marked enhancement of cerebral blood flow in areas of normal and disturbed circulation [see 5].
KeywordsStarch Ischemia Mannitol Lution Dextran
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