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Comparisons of Regional Topography and Flow Reactivity in Cerebral Ischemic Boundary Zones

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Cerebral Ischemia and Hemorheology

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Abstract

Although the term “penumbra” has been used since 1977 [1] to describe an ischemic boundary zone characterized by suppression of electrophysiological function with complete or near-complete preservation of extracellular potassium homeostasis, there is continued uncertainty regarding its nature and extent, and hence its significance in relation to the management of cerebral ischemia as it presents in man.

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References

  1. Astrup J, Symon L, Branston NM, Lassen NA (1977) Cortical evoked potential and extracellular K + and H + at critical levels of brain ischaemia. Stroke 8: 51–57

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Author information

Author notes

  1. A. J. Strong & S. A. Miller

    Present address: The Neurosurgical Unit, The Maudsley Hospital, SE5 8AZ, Denmark Hill, London, UK

  2. G. S. Venables

    Present address: Neurological Unit, Royal Hallamshire Hospital, Sheffield, UK

Authors and Affiliations

  1. Departments of Surgery (Neurosurgery) and Neurology, (GSV), University of Newcastle-Upon-Tyne, Newcastle, UK

    A. J. Strong, S. A. Miller & G. S. Venables

Authors
  1. A. J. Strong
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  2. S. A. Miller
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  3. G. S. Venables
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Editor information

Editors and Affiliations

  1. Neurologische Universitätsklinik, Sigmund-Freud-Str. 25, D-5300, Bonn 1, Germany

    Alexander Hartmann

  2. Physiologisches Institut I, Universität Bonn, Nußallee II, D-5300, Bonn 1, Germany

    Wolfgang Kuschinsky

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© 1987 Springer-Verlag Berlin Heidelberg

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Strong, A.J., Miller, S.A., Venables, G.S. (1987). Comparisons of Regional Topography and Flow Reactivity in Cerebral Ischemic Boundary Zones. In: Hartmann, A., Kuschinsky, W. (eds) Cerebral Ischemia and Hemorheology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71787-1_41

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  • DOI: https://doi.org/10.1007/978-3-642-71787-1_41

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71789-5

  • Online ISBN: 978-3-642-71787-1

  • eBook Packages: Springer Book Archive

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