Vascular Risk Factors in Progressive Low Tension Glaucoma
We have performed fundus fluorescein angiography in seventy-six patients with low tension glaucoma (M IOP in diurnal curve generally 20, maximum IOP peak 26 mm Hg).
We have described (to be published) the typical angiographic features of senile sclerotic glaucoma. In this investigation we examined the fluorescein angiographic differences in patients with LTG with and without progressive visual field defects. The follow-up period for these patients was at least three years. A separate group with a follow-up of seven years was also studied. A statistically significant difference in the duration of the arterial phase was found in the progressive and nonprogressive group. 68% of the patients in this progressive group had an arterial phase longer than two seconds opposite to only 35% on the non-progressive group. We also found a difference in the choroidal filling time in the two groups. The filling pattern in the two groups indicated a slow filling of the choroid in a large number of cases. It was, however, not different in these two groups.
It is concluded that vascular factors are playing an important role in the progression of LTG and that the fluorescein angiogram can be used for discovering these vascular risk factors in LTG.
KeywordsArterial Phase Fluorescein Angiography Primary Open Angle Glaucoma Progressive Group Primary Open Angle Glaucoma
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