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Plasma Exchange and Its Development in the Treatment of Familial Hypercholesterolemia

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Expanding Horizons in Atherosclerosis Research

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Abstract

The treatment of patients with homozygous familial hypercholesterolemia (FH) is a difficult and daunting clinical problem. Diet and drugs have little influence on the hypercholesterolemia of these patients; combinations of cholestyramine and nicotinic acid [1], compactin [2] and probucol [3] have also been tried but all have failed to provide adequate and satisfactory control of the disease. More recently mevinolin, a specific HMG-CoA reductase inhibitor, has produced good results in the treatment of heterozygous FH [4], but data on the homozygous form are still lacking.

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Authors
  1. M. Mancini
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  2. A. Postiglione
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  3. A. Gnasso
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Editor information

Editors and Affiliations

  1. Klinisches Institut für Herzinfarktforschung, Medizinische Universitätsklinik Bergheimer, Straße 58, 6900, Heidelberg, Germany

    Günter Schlierf

  2. Innere Abteilung am Diakonissenkrankenhaus Mannheim, Speyerer Straße 91-93, 6800, Mannheim 1, Germany

    Hubert Mörl

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© 1987 Springer-Verlag Berlin Heidelberg

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Mancini, M., Postiglione, A., Gnasso, A. (1987). Plasma Exchange and Its Development in the Treatment of Familial Hypercholesterolemia. In: Schlierf, G., Mörl, H. (eds) Expanding Horizons in Atherosclerosis Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71753-6_46

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  • DOI: https://doi.org/10.1007/978-3-642-71753-6_46

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71755-0

  • Online ISBN: 978-3-642-71753-6

  • eBook Packages: Springer Book Archive

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