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Vascular Growth Factors and Atherogenesis in Diabetes Mellitus

  • T. Koschinsky
  • F. A. Gries

Abstract

Severe and premature atherosclerosis often occurs in type 1 as well as in type 2 diabetic patients. The diabetes-specific reasons for this are still poorly understood [1]. Within the various pathomechanisms that are involved in the development of macrovascular disease, alterations in the growth of arterial wall cells have received increased attention, and abnormally increased growth of vacular cells is well-established as an intrinsic part of atherogenesis [2]. This paper will focus on the potential relevance of vascular growth stimulating factors that could initiate or accelerate growth of human arterial wall cells, in relation to atherogenesis in diabetes mellitus.

Keywords

Growth Effect Arterial Smooth Muscle Cell Poor Metabolic Control Vascular Growth Factor Human Arterial Smooth Muscle Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • T. Koschinsky
  • F. A. Gries

There are no affiliations available

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