Abstract
It can be estimated that in man a minimum of 1 g cholesterol day-1 must be removed from peripheral tissues and conveyed ultimately to the liver for processing and/or excretion. Only a small proportion of cells of extrahepatic tissues is in direct contact with blood plasma that is the main route of transport to the liver; most of those cells are separated from the bloodstream by several barriers that do not favour free flow of fluids and some of them also restrict diffusion.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Reichl D, Miller NE (1986) The anatomy and physiology of reverse cholesterol transport. Clin Sci 70:221–231
Reichl D, Forte TM, Hong J-L, Rudra DN, Pflug JJ (1985) Human lymphedema fluid lipoproteins: particle size, cholesterol and apolipoprotein distribution and electron microscopic structure. J Lipid Res 26:1399–1415
Nichols AV, Blanche PJ, Gong EL, Shore VG, Forte TM (1985) Molecular pathways in the transformation of model discoidal lipoprotein complexes induced by lecithin: cholesterol acyltransferase. Biochem Biophys Acta 834:285–300
Kruth HS (1985) Subendothelial accumulation of unesterified cholesterol — an early event in atherosclerotic lesion. Atherosclerosis 57:337–341
Portman OW, Alexander M (1972) Changes in arterial subfractions with aging and atherosclerosis. Biochem Biophys Acta 260:460–474
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Reichl, D. (1987). Initial Stages of Reverse Transport of Cholesterol. In: Paoletti, R., Kritchevsky, D., Holmes, W.L. (eds) Drugs Affecting Lipid Metabolism. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71702-4_42
Download citation
DOI: https://doi.org/10.1007/978-3-642-71702-4_42
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-71704-8
Online ISBN: 978-3-642-71702-4
eBook Packages: Springer Book Archive