Cellular and Molecular Biology of Apolipoproteins: Receptor-Mediated Regulation of Cholesterol Metabolism

  • R. W. Mahley
Conference paper
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)


Lipoprotein receptors, especially those within the liver, play a central role in the regulation of cholesterol metabolism. Specific apolipoproteins (apo-) serve as the ligands for these receptors (for review, see Brown and Goldstein 1983, 1986; Mahley and Innerarity 1983; Mahley et al. 1984).


Cholesterol Metabolism Lipoprotein Receptor Cholesterol Homeostasis Chylomicron Remnant Human Apolipoprotein 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • R. W. Mahley
    • 1
    • 2
  1. 1.The Gladstone Foundation Laboratories for Cardiovascular Disease, Cardiovascular Research Institute, Department of PathologyUniversity of CaliforniaSan FranciscoUSA
  2. 2.The Gladstone Foundation Laboratories for Cardiovascular Disease, Cardiovascular Research Institute, Department of MedicineUniversity of CaliforniaSan FranciscoUSA

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