Abstract
H-ras, K-ras and N-ras are members of a family of highly homologous vertebrate proto-oncogenes that code for a protein of 189 amino acids. The p21 protein products of the viral v-H-ras and v-K-ras genes are the causing agents of rat sarcomas and mutated forms of all three ras proto-oncogenes have been shown to be contained in several human tumours and tumour cell lines and to be able to transform malignantly NIH3T3 fibroblasts ((1,2) for review).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bishop JM (1985) Trends Genet 1:245–249
Levinson AD (1986) Trends Genet 2:81–85
Gibbs JB, Sigal IS, Scolnick EM (1985) Trends Biochem Sci 10:350–353
Gallwitz D, Donath C, Sander C (1983) Nature (London) 306:704–707
DeFeo-Jones D, Scolnick EM, Koller R, Dhar R (1983) Nature (London) 306:707–709
Powers S, Kataoka T, Fasano O, Goldfarb M, Strathern J, Broach J, Wigler M (1984) Cell 36:607–612
Toda T, Uno I, Ishikawa T, Powers S, Kataoka T, Broek D, Cameron S, Broach J, Matsumoto K, Wigler M (1985) Cell 40:27–36
Uno I, Mitzusawa H, Matsumoto K, Tanaka K, Oshima T, Ishikawa T (1985) Proc Natl Acad Sci USA 82:7855–7859
Beckner SK, Hattori S, Shih TY (1985) Nature (London) 317:71–72
Birchmeier C, Broek D, Wigler M (1985) Cell 43:615–621
Birchmeier C, Broek D, Wigler M (1985) Cell 43:615–621
Murray AW, Szostak JW (1983) Cell 34:961–970
Halliday K (1984) J Cyclic Nucleotide Prot Phosphoryl Res 9:435–448
Möller W, Amons R (1985) FEBS Lett 186:1–7
Tanabe T, Nukada T, Nishikawa Y, Sugimoto K, Suzuki H, Takahashi H, Noda M, Haga T, Ichiyama A, Kangawa K, Minamino N, Matsuo H, Numa S (1985) Nature (London) 315:242–245
Jurnak F (1985) Science 230:32–36
Fasano O, Aldrich T, Tamanoi F, Taparowsky E, Furth M, Wigler M (1984) Proc Natl Acad Sci USA 81:4008–4012
Seeburg PH, Colby WW, Capon JJ, Goeddel DV, Levinson AD (1984) Nature (London) 314:71–74
Yuasa Y, Srivastava SK, Dunn CY, Rhim JS, Reddy EP, Aaranson SA (1983) Nature (London) 303:775–779
Der CJ, Finkel T, Cooper GM (1986) Cell 44:167–176
Shih TY, Stokes PE, Smythers GV, Dhar R, Oroszian S (1982) J Biol Chem 257:11776–11773
McCormick F, Clark BFC, La Cour TFM, Kjelgaard M, Norskov-Lauritsen L, Nijborg J (1985) Science 230:78–82
Gibbs JB, Sigal IS, Poe M, Scolnick EM (1984) Proc Natl Adad Sci USA 81:5704–5708
Kataoka T, Powers S, Cameron S, Fasano O, Goldfarb M, Broach J, Wigler M (1985) Cell 40:19–26
DeFeo-Jones D, Tatchell K, Robinson LC, Sigal IS, Vass WC, Lowy DR, Scolnick EM (1985) Science 228:179–184
Fukui Y, Kozasa T, Kaziro Y, Takeda T, Yamamoto M (1986) Cell 44:329–336
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Gallwitz, D., Brökel, R., Molenaar, C.M.T., Rauh, A.J.G., Schmitt, H.D., Wagner, P. (1986). Functional Analysis of the ras-Related YPT1 Gene Product in Yeast. In: Tanner, W., Gallwitz, D. (eds) Cell Cycle and Oncogenes. Colloquium der Gesellschaft für Biologische Chemie 10.–12. April 1986 in Mosbach/Baden, vol 37. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71686-7_14
Download citation
DOI: https://doi.org/10.1007/978-3-642-71686-7_14
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-71688-1
Online ISBN: 978-3-642-71686-7
eBook Packages: Springer Book Archive