Functional Analysis of the ras-Related YPT1 Gene Product in Yeast

  • D. Gallwitz
  • R. Brökel
  • C. M. T. Molenaar
  • A. J. G. Rauh
  • H. D. Schmitt
  • P. Wagner
Conference paper
Part of the Colloquium der Gesellschaft für Biologische Chemie 10.–12. April 1986 in Mosbach/Baden book series (MOSBACH, volume 37)


H-ras, K-ras and N-ras are members of a family of highly homologous vertebrate proto-oncogenes that code for a protein of 189 amino acids. The p21 protein products of the viral v-H-ras and v-K-ras genes are the causing agents of rat sarcomas and mutated forms of all three ras proto-oncogenes have been shown to be contained in several human tumours and tumour cell lines and to be able to transform malignantly NIH3T3 fibroblasts ((1,2) for review).


GTPase Activity Spindle Pole Body Intrinsic GTPase Activity Autophosphorylating Activity Arrest Phenotype 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • D. Gallwitz
  • R. Brökel
  • C. M. T. Molenaar
  • A. J. G. Rauh
  • H. D. Schmitt
  • P. Wagner
    • 1
  1. 1.Physiologisch-Chemisches InstitutUniversität MarburgMarburgGermany

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