Abstract
The advances in gene technology with eukaryotic systems during the past 5 years has led to a considerable number of novel aspects on the function of DNA sequences which control transcription (promoters, terminators, regulators) of nuclear genes in lower eukaryotes. The mass of findings with regard to gene regulation has been obtained in baker’s yeast, Saccharomyces cerevisiae, and in a few other fungi and yeasts. From these studies it became very obvious that there are some basic differences in the mechanism of mRNA initiation and its regulation between prokaryotes and eukaryotes. This might not be surprising since prokaryotes lack an equivalent of the eukaryotic chromatin and a nucleus. However, in both systems it is a question of protein-nucleic acid interaction; that is to say the differences currently emerging can be largely viewed as variations of the same subject: how does a protein (RNA polymerase or a regulatory protein) recognize a specific site among thousands of other sites on the DNA.
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References
Beier, D.R., Young, E.T.: Nature (London) 300, 724–728 (1982)
Beier, D.R., Sledziewski, A., Young, E.T.: Mol. Cell. Biol. 5, 1743–1749 (1985)
Benoist, C., Chambon, P.: Nature (London) 290, 304–310 (1981)
Boeke, J.D., Garfinkel, D.J., Styles, C.A., Fink, G.R.: Cell 40, 491– 500 (1985)
Bram, R.J., Kornberg, R.D.: Proc. Natl. Acad. Sci. USA 82, 43–47 (1985)
Bram, R.J., Lue, N.F., Kornberg, R.D.: Embo J. 5, 603–608 (1986)
Brand, A.H., Breeden, L., Abraham, J., Sternglanz, R., Nasmyth, K.: Cell 41, 41–48 (1985)
Breatnach, R., Chambon, P.: Annu. Rev. Biochem. 50, 349–384 (1981)
Brent, R., Ptashne, M.: Nature (London) 312, 612–615 (1984).
Dobson, M.J., Tuite, M.F., Roberts, N.A., Kingsman, A.J., Kingsman, S.M., Perkins, R.E., Conroy, S.C., Dunbar, B., Fothergill, L.A.: Nucl. Acids Res. 10, 2625–2637 (1982)
Donahue, T.F., Davies, R.S., Lucchini G., Fink, G.R.: Cell 32, 89–98 (1983).
Errede, B., Company, M., Ferchak, J.D., Hutchinson, C.A., Yarnell, W. S.: Proc. Natl. Acad. Sci. USA 82, 5423–5427 (1985).
Faye, G., Leung, D., Tatchell, K., Hall, B.D., Smith, M.: Proc. Natl. Acad. Sci. USA 78, 2258–2262 (1981).
Garfinkel, D.J., Boeke, J.D., Fink, G.R.: Cell 42, 507–517 (1985)
Geever, R.F., Murayama, T., Case, M.E., Giles, N.: Proc. Natl. Acad. Sci. USA 83, 3944–3948 (1986)
Giniger, E., Varnum, S.M., Ptashne, M.: Cell 40, 767–774 (1985)
Guarantee, L.: Cell 36., 799–800 (1984).
Guarantee, L., Mason, T.: Cell 32, 1279–1286 (1983)
Guarantee, L., Yoccum, R.R., Giffard, P.: Proc. Natl. Acad. Sci. USA 79, 7410–7414 (1982)
Guarantee, L., Lalonde, B., Gifford, P., Alam, E.: Cell 36, 503–511 (1984).
Hartshorne, T.A., Blumberg, H., Young, E.T.: Nature (London) in press (1986)
Hippel, P.H. v., Bear, D.G., Morgan, W.D., Swiggen, J.A.: Annu. Rev. Biochem. 53, 389–445 (1984).
Johnson, A.D., Herskowitz, I. Cell 42, 237–247 (1985)
Johnston, M., Davis, R.W.: Mol. Cell. Biol. 4, 1440–1448 (1984).
Keegan, L., Gill, G., Ptashne, M.: Science 231, 699–704 (1986)
Kellermann, E., Seeboth, P.G., Hollenberg, C.P.: submitted (1986)
Khoury, G., Gruss, P.: Cell 33, 313–314 (1983)
Kingsman, S.M., Kingsman, A.J., Dobson, M.J., Mellor, J., Roberts, N.A.: Biotech. Genet. Eng. Rev. 3, 337–416 (1985).
Laughon, A., Gesteland, R.F.: Proc. Natl. Acad. Sci. USA 79, 6827–6831 ( 1982 )
Laughon, A., Scott, M.P.: Nature (London) 310, 25–29 (1984).
MCCLURE, W.R.: Annu. Rev. Biochem. 54, 171–204 (1985)
Mcneil, J.B., Smith, M.: J. Mol. Biol. 187, 363–378 (1986)
Mellor, J., Malim, M.H. Gull, K., Tuite, M.F., Mccready, S., Dibbayawan, T., Kingsman, S.M., Kingsman, A.J.: Nature (London) 318, 583–586 (1985).
Nagawa, F., Fink, G.R.: Proc. Natl. Acad. Sci. USA 82, 8557–8561 (1985)–Nasmyth, K.A.: Annu. Rev. Genet. 16, 439–500 (1982)
Nordheim, A., RICH, A.: Nature (London) 303, 674–678 (1983).
Oshima, Y.: 159–180 in: Molecular Biology of the Yeast Saccharomyces, eds. J. Strathern, E. Jones, J.R. Broach, Vol. I. New York: Cold Spring Harbor Laboratory Press 1982.
Perlman, D., Hopper, J.E.: Cell 16, 89–95 (1979).
Roeder, G.S., Rose, A.B., Pearlman, R.E.: Proc. Natl. Acad. Sci. USA 82, 5428–5432 (1985)
Roman, H.: 1–10 in: Molecular Biology of the Yeast Saccharomyces, eds. J. Strathern, E. Jones, J.R. Broach, Vol. I. New York: Cold Spring Harbor Laboratory Press 1982.
Sentenac, A., Hall, B.D.: 561–606 in: Molecular Biology of the Yeast Saccharomyces, eds. J. Strathern, E. Jones, J.R. Broach, Vol. II. New York: Cold Spring Harbor Laboratory Press 1982
Shepherd, J.C.W., Mcginnis, W., Carrasco, A.E., de Robertis, E.M., Gehring, W. : Nature (London) 310, 70–71 (1 983)
Siliciano, P.G., Tatchell, K.: Cell 37, 969–978 (1984)
Silver, P.A., Keegan, L.P., Ptashne, M.: Proc. Natl. Acad. Sci. USA 81, 5951–5955 (1984)
St. John, T.P., Davis, R.W.: J. Mol. Biol. 152, 285–315 (1981 )
Struhl, K.: Nature (London) 300, 284–286 (1982); - Proc. Natl. Acad. Sci. USA 81, 7865–7869 (1984).
Taguchi, A.K.W., Ciriacy, M., Young, E.T.: Mol. Cell. Biol. 4, 61–68 ( 1984) .
West, R.W., Yoccum, R.R., Ptashne, M.: Mol. Cell. Biol. 4, 2467–2478 ( 1984 )
Williamson, V.M.: Int. Rev. Cy tol. 83, 1–25 (1983).
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© 1986 Springer-Verlag Berlin Heidelberg
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Ciriacy, M. (1986). Function of the Genetic Material: Structure and Function of Elements Controlling Transcription in Lower Eukaryotes. In: Behnke, HD., Esser, K., Kubitzki, K., Runge, M., Ziegler, H. (eds) Progress in Botany. Progress in Botany/Fortschritte der Botanik, vol 48. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71668-3_15
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DOI: https://doi.org/10.1007/978-3-642-71668-3_15
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