Abstract
In vivo fibrinogen, fibrin and the degradation products may play an important role for example in peritonitis and in ARDS. Formation of edema and of fibrosis might be due to the effects of these substances. In co-cultures of human endothelial cells and fibrocytes/fibroblasts we want to elucidate the role of fibrinogen, fibrin and the degradation products under wound healing conditions. It turns out that these substances may influence proliferation of cells in co-culture adversely in a dose-dependent manner.
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References
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© 1986 Springer-Verlag Berlin Heidelberg
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Franke, R.P., Dauer, U., Müllners, W., Fuhrmann, R., Mittermayer, C. (1986). Simulation of Wound Healing in Cell Cultures Given that Fibrin Sealant Is Present. In: Schlag, G., Redl, H. (eds) Fibrin Sealant in Operative Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71633-1_34
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DOI: https://doi.org/10.1007/978-3-642-71633-1_34
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-17141-6
Online ISBN: 978-3-642-71633-1
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