Experience with Fibrin Glue (Tissucol/Tisseel) in Vascular Surgery

Abstract

We consider fibrin glue a useful aid in vascular surgery. It has proven particularly helpful as a hemostatic and tissue sealant agent. Fibrin glue has been used by authors to control difficult bleeding on vascular anastomoses, especially on small and calcified vessels, to obtain hemostasis in heparinized patients or in those with coagulopathies, to permit the use of highly porous vascular prostheses even in anticoagulated patients, to control residual bleeding after embolization and surgical resection of angiodisplasias and to obtain the thrombosis of an expanding abdominal aortic aneurysm in a very high risk patient. Fibrin glue is considered an effective aid, in many and various instances decreasing the need for blood transfusions and shortening operating time.