Abstract
From 1978 to April 1985, fibrin sealant was applied in a group of 756 patients undergoing extracorporeal circulation, whenever conventional suturing methods were impossible, difficult or dangerous. The success rate was 97%. Fibrin sealant combined with antibiotics was proved to be potentially helpful for use with vascular and cardiac valve prostheses in infected areas.
In addition fibrin presealed woven or knitted grafts were inserted in 138 patients undergoing extracorporeal circultation, in which 127 underwent cardiac procedures. The failure rate was less than 5%. Fibrin adhesive has become a universally effective and reliable method of bleeding control. Fibrin presealed knitted prostheses are expected to replace woven fabric in the future because of its known poor healing qualities.
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Haverich, A., Wahlers, T., Walterbusch, G., Borst, H.G. (1986). The Use of Fibrin Sealant and Fibrin Sealant Combined with Antibiotics in Cardiovascular Surgery. In: Schlag, G., Redl, H. (eds) Fibrin Sealant in Operative Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71633-1_29
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DOI: https://doi.org/10.1007/978-3-642-71633-1_29
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-17141-6
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