Abstract
An occlusion of the bronchus stump following pneumonectomy was achieved by using only fibrin sealant transthoracically in 14 domestic pigs. Standardized bronchus stump fistulae could also be closed with the fibrin sealant, which was applied through a flexible bronchoscope in ten additional animals. An average quantity of 1ml fibrin sealant containing 500 units thrombin and 3000 units aprotinin was necessary for the bronchial closure and to prevent early dissolution of the fibrin clot. This endoscopic method was already employed successfully in one clinical case of a bronchus stump fistula.
The bronchus stump fistula is one of the most dreaded complications following pneumonectomy. Since the use of mechanical staplers the rate of this complication has been definitely decreased. But once a fistula occurs its treatment is unsatisfactory. In this experimental study we evaluated the feasibility of an endoscopic occlusion of bronchus stump fistulae by fibrin plugs.
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References
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© 1986 Springer-Verlag Berlin Heidelberg
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Waclawiczek, H.W., Chmelizek, F. (1986). Endoscopic Occlusion of Bronchus Stump Fistulae Following Pneumonectomy with Fibrin Sealant in Animal Experiments. In: Schlag, G., Redl, H. (eds) Fibrin Sealant in Operative Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71633-1_18
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DOI: https://doi.org/10.1007/978-3-642-71633-1_18
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-17141-6
Online ISBN: 978-3-642-71633-1
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