Abstract
The olfactory mucosa of vertebrates contains secretory elements that produce a layer of mucus that covers the surface of the olfactory epithelium (Graziadei 1971; Yamamoto 1982). The secretions presumably play a role in olfactory function by (a) providing the ionic and macromolecular environment in which odorants interact with their receptor sites on the olfactory receptor neurons (Bannister 1974; TV Cetchell and ML Getchell 1977), (b) affecting access of odorants to the epithelial surface (Mozell 1971; Bostock 1974) and (c) facilitating odorant removal (Hornung and Mozell 1981; TV Getchell et al. 1985).
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Bakhtin YK (1976) Morphology of the olfactory organ of some fish species and a possible functional interpretation. J Ichthyol 16: 786–804
Bang BG (1964) The mucous glands of the developing human nose. Acta Anat 59: 297–314
Bannister LK (1974) Possible functions of mucus at gustatory and olfactory surfaces. In: Poynder TM (ed) Transduction mechanisms in chemoreception. IRL Press, London, pp 39–46
Bertmar C (1973) Ultrastructure of the olfactory mucosa in the homing Baltic Sea trout Salmo trutta trutta. Mar Biol 19: 74–88
Bostoch H (1974) Diffusion and the frog EOG. In: Poynder TM (ed) Transduction mechanisms in chemoreception. IRL Press, London, pp 27–38
Breipohl W (1972) Licht- und elektronenmikroskopische Befunde zur Struktur der Bowmanschen Drüsen in Riechepithel der weißen Maus. Z Zellforsch 131: 329–346
Breipohl W, Fernandez M (1977) Scanning electron microscopic investigations of olfactory epithelium in the chick embryo. Cell Tissue Res 183: 105–114
Breipohl W, Bijvank GJ, Zippel HP (1973a) Die Oberflächenstruktur der olfaktorischen Drüsen des Goldfisches (Carassius auratus). Eine rastermikroskopische Studie. Z Zellforsch 140: 567–582
Breipohl W, Mestres P, Meller K (1973b) Licht- und elektronenmikroskopische Befunde zur Differenzierung des Riechepithels der weißen Maus. Verh Anat Ges 67: 443–449
Breipohl W, Moulton D, Ummels M, Matulionis DH (1982) Spatial pattern of sensory cell terminals in the olfactory sac of the tiger salamander. I. A scanning electron microscope study. J. Anat 134: 757–769
Bücher U, Reid L (1961) Development of the mucus-secreting elements in human lung. Thorax 16: 219–225
Cuschieri A, Bannister LH (1975a) The development of the olfactory mucosa in the mouse: light microscopy. J Anat 119: 277–286
Cuschieri A, Bannister LH (1975b) The development of the olfactory mucosa in the mouse: electron microscopy. J Anat 119: 471–498
Filyushina YY, Bakhmin YK (1975) Electron-microscopic investigation of the olfactory epithelium of the Baikal omul Coregonus autumnalis migratorius. J Ichthyol 15: 284–290
Getchell ML, Getchell TV (1984a) β-Adrenergic regulation of the secretory granule content of acinar cells in olfactory glands of the slamander. J Comp Physiol A 155: 435–443
Getchell ML, Getchell TV (1984b) Cholinergic control of glandular secretion in the olfactory mucosa of the salamander. In: Abstr Proc Annu Meet Assoc Chemoreception Sci, Sarasota, FL
Getchell ML, Rafols JA, Getchell TV (1984) Histological and histochemical studies of the secretory components of the salamander olfactory mucosa: Effects of isoproterenol and olfactory nerve section. Anat Rec 208: 553–565
Getchell TV (1977) Analysis of intracellular recordings from salamander olfactory epithelium. Brain Res 123: 275–286
Getchell TV, Getchell ML (1977) Histochemical localization and identification of secretory products in salamander olfactory epithelium. In: LeMagnen J, MacLeod P (eds) Olfaction and taste, vol VI. IRL Press, London, pp 105–112
Getchell TV, Zielinski B, Getchell ML (1985) Pyrazine-mediated neural and secretory activity in the olfactory mucosa of the salamander (abstr). Chem Sens 10: 398
Graziadei PPC (1971) The olfactory mucosa of vertebrates. In: Beidler LM (ed) Handbook of sensory physiology, vol IV. Chemical senses 1. Olfaction. Springer, Berlin Heidelberg New York, pp 27–58
Graziadei PPC, Monti Graziadei GA (1976) Olfactory epithelium of Necturus maculosus and Ambystoma tigrinum. J Neurocytol 5: 11–32
Hafez ESE (1977) Functional anatomy of mucus-secreting cells. In: Elstein M, Parke DV (eds) Mucus in health and disease. Plenum Press, New York, pp 19–34
Herberhold C (1968) Vergleichende histochemische Untersuchungen am peripheren Riechorgan von Säugetieren und Fischen. Arch Klin Exp Ohr Nas Kehlk Heilkd 190: 166–182
Hornung DE, Mozell MM (1981) Accessibility of odorant molecules to the receptors. In: Cagan RH, Kare MR (eds) Biochemistry of taste and olfaction. Academic Press, London New York, pp 33–45
Kauer JS (1981) Olfactory receptor cell staining using horseradish peroxidase. Anat Rec 200: 331–336
Kleerekoper H (1969) Olfaction in Fishes. Indiana Univ Press, Bloomington
Klein SL, Graziadei PPC (1983) The differentiation of the olfactory placode in Xenopus laevis: a light and electron microscope study. J Comp Neurol 217: 17–30
Masukawa LM, Kauer JS, Shepherd GM (1983) Intracellular recordings from two cell types in an in vitro preparation of the salamander olfactory epithelium. Neurosci Lett 35: 59–64
Masukawa LM, Hedlund B, Shepherd GM (1985a) Electrophysiological properties of identified cells in the in vitro olfactory epithelium of the tiger salamander. J Neurosci 5: 128–135
Masukawa LM, Hedlund B, Shepherd GM (1985b) Changes in the electrical properties of olfactory epithelial cells in the tiger salamander after olfactory nerve transection. J Neurosci 5: 136–141
Mozell MM (1971) Spatial and temporal patterning. In: Beidler LM (ed) Handbook of sensory physiology, vol IV. Chemical senses 1. Olfaction. Sringer, Berlin Heidelberg New York, pp 205–215
Ojha PP, Kapoor AS (1972) Histochemistry of the olfactory epithelium of the fish, Canna punctatus Bloch. Acta Anat 83: 540–555
Okano M, Takagi SF (1974) Secretion and electrogenesis of the supporting cell in the olfactory epithelium. J Physiol (London) 242: 353–370
Pyatkina CA (1982) Development of the olfactory epithelium in man. Z Mikrosk Anat Forsch Leibzig 96: 361–372
Rafols JA, Getchell TV (1983) Morphological relations between the receptor neurons, sustentacular cells and Schwann cells in the olfactory mucosa of the salamander. Anat Rec 206: 87–101
Scifert K (1971) Licht- und elektronenmikroskopische Untersuchungen der Bowman-Drüsen in der Riechschleimhaut makrosmatischer Säuger. Arch Klin Exp Ohr Nas Kehlk Heilkd 200: 252–274
Simmons PA, Rafols JA, Getchell TV (1981) Ultrastructural changes in olfactory receptor neurons following olfactory nerve section. J Comp Neurol 197: 237–257
Spicer SS, Chakrin LW, Wardell JR Jr, Kendrick W (1971) Histochemistry of mucosubstances in the canine and human respiratory tract. Lab Invest 25: 483–490
Thaete LG, Spicer SS, Spock A (1981) Histology, ultrastructure, and carbohydrate cytochemistry of surface and glandular epithelium of human nasal mucosa. Am J Anat 162: 243–263
Theisen B, Breucker H, Zeiske E, Melinkat R (1980) Structure and development of the olfactory organ in the garfish Belone belone (L.) (Teleostei, Atheriniformes) Acta Zool (Stockholm) 61: 161–170
Tos M (1982) Goblet cells and glands in the nose and paranasal sinuses. In: Proctor DF, Andersen I (eds) The nose. Upper airway physiology and the atmospheric environment. Elsevier Biomedical Press, Amsterdam New York Oxford, p 99
Tos M, Poulsen J (1975) Mucous glands in the developing human nose. Arch Otolaryngol 101: 367–372
Trotier D, MacLeod P (1983) Intracellular recordings from salamander olfactory cells. Brain Res 268: 225–237
Yamamoto M (1982) Comparative morphology of the peripheral olfactory organ in teleosts. In: Hara TJ (ed) Chemoreception in fishes. Elsevier, Amsterdam, pp 39–59
Zeiske E, Melinkat R, Breucker H, Kux J (1976) Ultrastructural studies of the epithelia of the olfactory organ of cyprinodonts (Teleostei, Cyprinodontoidea). Cell Tissue Res 172: 245–267
Zielinski B (1985) Morphological and physiological studies of the development of the peripheral olfactory organ in rainbow trout, Salmo gairdneri. Thesis, Univ. Manitoba, Winnipeg
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Getchell, M.L., Zielinski, B., Getchell, T.V. (1986). Ontogeny of the Secretory Elements in the Vertebrate Olfactory Mucosa. In: Breipohl, W., Apfelbach, R. (eds) Ontogeny of Olfaction. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71576-1_6
Download citation
DOI: https://doi.org/10.1007/978-3-642-71576-1_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-71578-5
Online ISBN: 978-3-642-71576-1
eBook Packages: Springer Book Archive