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In-vitro-Fertilisierung und Embryotransfer

  • Chapter
Gynäkologische Endokrinologie

Zusammenfassung

Die Idee, eine eileiterbedingte Sterilität mit Hilfe der extrakorporalen Befruchtung zu behandeln, ist keineswegs neu. Bereits 1937 hatte ein anonymer Autor im angesehenen „New England Journal of Medicine“ die spätere Entwicklung unter dem Titel „Conception in a watch-glass“ vorhergesagt. Bis diese Vision durch die Geburt des ersten so gezeugten Kindes verwirklicht werden konnte, sollten aber noch über 40 Jahre vergehen.

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Literatur

  • Anonymus (1937) Conception in a watch-glass. N Engl J Med 217: 678

    Article  Google Scholar 

  • Austin CR (1951) Observations on the penetration of the sperm into the mammalian egg. J Sci Rcs Ser B 4: 581–596

    CAS  Google Scholar 

  • Biggers JD, Brinster RL (1965) Biometrical problems in the study of early mammalian embryos in vitro. J Exp Zool 158: 39–48

    Article  PubMed  CAS  Google Scholar 

  • Blandau RJ (1980) In vitro fertilization and embryo transfer. Fertil Steril 33: 3–11

    PubMed  CAS  Google Scholar 

  • Brinster RL (1965a) Studies on the development of mouse embryos in vitro. I. The effect of osmolarity and hydrogen ion concentration. J Exp Zool 158: 49–58

    Article  PubMed  CAS  Google Scholar 

  • Brinster RL (1965b) Studies on the development of mouse embryos in vitro. II. The effect of energy source. J Exp Zool 158: 59–65

    Article  PubMed  CAS  Google Scholar 

  • Brinster RL (1965c) Studies on the development of mouse embryos in vitro. III. The effect of fixed nitrogen source. J Exp Zool 158: 69–78

    Article  PubMed  CAS  Google Scholar 

  • Brinster RL (1965c) Studies on the development of mouse embryos in vitro. IV. Interaction of energy sources. J Reprod Fertil 10: 227–240

    Article  PubMed  CAS  Google Scholar 

  • Brown JB (1955) A chemical method for the determination of oestriol, oestrone and oestradiol in human urine. Biochem J 60: 185–193

    PubMed  CAS  Google Scholar 

  • Chang MC (1951) Fertilizing capacity of spermatozoa deposited into the fallopian tubes. Nature 168: 697–698

    Article  PubMed  CAS  Google Scholar 

  • Chang MC (1959) Fertilization of rabbit ova in vitro. Nature 184: 466–467

    Article  PubMed  Google Scholar 

  • Craft I, McLeod F, Edmonds K (1981) Human embryo transfer technique. Lancet II: 1104–1105

    Article  Google Scholar 

  • De Kretzer D, Dennis P, Hudson B et al. (1973) Transfer of a human zygote. Lancet II:728–729

    Article  Google Scholar 

  • Drake TS, Grunert GM (1980) The unexpected pelvic factor in the infertility investigation. Fertil Steril 34: 27–31

    PubMed  CAS  Google Scholar 

  • Edwards RG (1981) Test-tube babies, 1981. Nature (Lond) 293: 253–256

    Article  CAS  Google Scholar 

  • Edwards RG, Steptoe PG (1980) A matter of life. Hutchinson, London

    Google Scholar 

  • Edwards RG, Steptoe RC, Purdy JM (1980) Establishing full-term human pregnancies using cleaving embryos grown in vitro. Br J Obstet Gynaecol 87: 737–756

    Article  PubMed  CAS  Google Scholar 

  • Edwards RG, Anderson G, Pickering J, Purdy JM (1982) Rapid assay of urinary LH in women using a simplified method of Hi-Gonavis. In: Edwards RG, Purdy JM (eds) Human conception in vitro. Academic, London, pp 19–34

    Google Scholar 

  • Edwards RG, Fishel SB, Cohen J, Fehilly CB, Purdy JM, Slater JM, Septoe PC, Webster LM (1984) Factors influencing the success of in vitro fertilization for alleviating human infertility. J in vitro Fertilization Embryo Transfer 1: 3–23

    Article  CAS  Google Scholar 

  • Feichtinger W, Kemeter P, Szalay S (1984) Preovulatory serum estradiol-17ß values and ultrasound scans in 17 pregnacies which followed in vitro fertilization and embryo transfer after treatment with clomiphene and hCG. Arch Gynecol 234: 213–217

    Article  PubMed  CAS  Google Scholar 

  • Garcia J, Jones GS, Acosta AA, Wright GL (1981) Corpus luteum function after follicle aspiration for oocyte retrieval. Fertil Steril 36: 565–572

    PubMed  CAS  Google Scholar 

  • Gomel V (1978) Salpingostomy by microsurgery. Fertil Steril 29: 380–387

    PubMed  CAS  Google Scholar 

  • Habermann PG, Hünlich T, Kreuzer E, Trotnow S (1984) Schwangerschaft nach ultraschallkontrollierter transabdominal-transvesikaler Follikelpunktion in Periduralanästhesie im Rahmen eines IVF-Programmes. Geburtshilfe Frauenheilkd 44: 667–669

    Article  PubMed  CAS  Google Scholar 

  • Hackelöer BJ, Robinson HP (1978) Ultraschalldarstellung des wachsenden Follikels and Corpus luteum im normalen physiologischen Zyklus. Geburtshilfe Frauenheilkd 38: 163–168

    PubMed  Google Scholar 

  • Halme J, Becker S, Hammond MG, Raj S (1982) Pelvic macrophages in normal and infertile women: the role of patent tubes. Am J Obstet Gynecol 142: 890

    PubMed  CAS  Google Scholar 

  • Hammond J (1949) Recovery and culture of tubal mouse ova. Nature 163: 28–29

    Article  PubMed  Google Scholar 

  • Heape W (1980) Preliminary note on the transplantation and growth of mammalian ova within an uterine foster-mother. Proc R Soc Lond 48: 457–458

    Google Scholar 

  • Hoppe PC, Pitts S (1973) Fertilization in vitro and de- velopment of mouse ova. Biol Reprod 8: 420–426

    PubMed  CAS  Google Scholar 

  • Hünlich T, Trotnow S, Mulz D, Kniewald T (1984) Hormonal and ultrasonic characteristics of 23 clomiphene citrate stimulated cycles resulting in pregnancies after in vitro fertilization and embryo transfer. Arch Gynecol 236: 19–23

    Article  PubMed  Google Scholar 

  • Hull MGR, Savage IPE, Bromham DR (1982) Prognostic value of the postcoital test. Prospective study based on time-specific conception rates. Br J Obstet Gynaecol 89: 299

    Article  PubMed  CAS  Google Scholar 

  • Jones HW Jr (1983) Factors influencing implantation and maintenace of pregnancy following embryo transfer. In: Beier HM, Lindner HR (eds) Fertilization of the human egg in vitro: biological basis and clinical applications. Springer, Berlin Heidelberg New York, pp 293–306

    Google Scholar 

  • Jones HW Jr, Acosta AA, Garcia J (1982a) A technique for the aspiration of oocytes from human ovarian follicles. Fertil Steril 37: 26–29

    PubMed  Google Scholar 

  • Jones HW Jr, Jones GS, Andrews MC, Acosta AA, Bundren C, Garcia J, Sandow BA, Veeck L, Wilkes C, Witmeyer J, Wortham JE, Wright G (1982b) The program for in vitro fertilization at Norfolk. Fertil Steril 38: 14

    PubMed  Google Scholar 

  • Jones HW Jr, Acosta AA, Garcia JE, Sandow BA, Veeck L (1983) On the transfer of conceptuses from oocytes fertilized in vitro. Fertil Steril 39: 241–243

    PubMed  Google Scholar 

  • Laufer N, et al. (1983) The use of high dose human menopausal gonadotropin in an in vitro fertilization program. Fertil Steril 40: 734–741

    PubMed  CAS  Google Scholar 

  • Leeton J, Trounson A, Jessup D, Wood C (1982) The technique for human embryo transfer. Fertil Steril 38: 156–161

    PubMed  CAS  Google Scholar 

  • Lehmann F, Diedrich K, van der Ven H, Al-Hasani S, Schulz Ch, Krebs D (1983a) Induced luteal defect after follicle aspiration. In: Taubert HD, Kuhl H (eds) The inadequate luteal phase. MTP, Lancaster, pp 39–47

    Google Scholar 

  • Lehmann F, Diedrich K, van der Ven H, Al-Hasani S, Krebs D (1983b) Die Lutealphase nach Follikelpunktion. Geburtshilfe Frauenheilkd 43: 305–312

    Article  Google Scholar 

  • Lenz S, Lauritzen JG, Kjellow M (1981) Collection of human oocytes for in vitro fertilization by ultrasonically guided follicular puncture. Lancet I:1163

    Article  Google Scholar 

  • Lenz S, Lauritzen JG (1982) Ultrasonically guided precutaneous aspiration of human follicles under local anesthesia: a new method to collect oocytes for in vitro fertilization. Fertil Steril 38: 673

    PubMed  CAS  Google Scholar 

  • Leung PCS, Gronow MJ, Kellow, GN, Lopata A, Speirs AL, McBain JC, du Plessis YP, Johnston I (1984) Serum supplement in human in vitro fertilization and embryo development. Fertil Steril 41: 36–39

    PubMed  CAS  Google Scholar 

  • Lopata A, Brown JB, Leeton JF, Talbot J, Wood C (1978) In vitro fertilization of preovulatory oocytes and embyo transfer in infertile patients treated with clomiphene and chorionic gonadotropin. Fertil Steril 30: 27–35

    PubMed  CAS  Google Scholar 

  • Lopata A, Johnston JWH, Hoult IJ, Speirs A (1980) Pregnancy following intrauterine implantation of an embryo obtained by in vitro fertilization of a preovulatory egg. Fertil Steril 33: 642–643

    Google Scholar 

  • Maas DHA, Storey BT, Mastroianni L Jr (1976) Oxygen tension in the oviduct of the rhesus monkey. Fertil Steril 27: 1312–1316

    PubMed  CAS  Google Scholar 

  • Nilson L, Hamberger L, Janson PO, Wikland M (1982) Are repeated hormone determinations necessary for the prediction of the exact time of induced ovulations? In: Beier HM, Lindner HR (eds) Fertilization of the human egg in vitro: biological basis and clinical applications. Springer, Berlin Heidelberg New York, pp 95–97

    Google Scholar 

  • Olson JL, Rebar RW, Schreiber JR, Vaitukaitis JL (1983) Shortened luteal phase after ovulation induction with human menopausal gonadotropin and human chorionic gonadotropin. Fertil Steril 39: 284–291

    PubMed  CAS  Google Scholar 

  • Onanoff J (1893) Recherche sur la fecondation et la gestation des mammiferes. C R Soc Biol (Paris) 45: 719

    Google Scholar 

  • Pincus G (1930) Observations on the living eggs of the rabbit. Proc R Soc Lond (Biol) 107: 132–167

    Article  Google Scholar 

  • Pincus G, Entzmann EV (1934) Can mammalian eggs undergo normal development in vitro? Proc Natl Acad Sci USA 20: 121–122

    Article  PubMed  CAS  Google Scholar 

  • Renou P, Trounson AO, Wood C, Leeton JF (1981) The collection of human oocytes for in vitro fertilization. I. An instrument for maximizing oocyte recovery rate. Fertil Steril 35: 409–412

    PubMed  CAS  Google Scholar 

  • Rock J, Menkin MF (1944) In vitro fertilization and cleavage of human ovarian eggs. Science 100: 105–107

    Article  PubMed  CAS  Google Scholar 

  • Saito M, et al. (1983) Microassay for urine estrogens by competitive hemagglutination inhibition reaction. Wld Obstet Gynecol 35: 939–943

    CAS  Google Scholar 

  • Schenk SL (1878) Das Säugetierei künstlich befruchtet außerhalb des Muttertieres. Mittl Embryol Instit KK Univ Wien I:107

    Google Scholar 

  • Seppälä M (1984) Vortrag auf dem III. World congress of in vitro fertilization and embryo transfer, Helsinki, 14.5.–17.5. 1984

    Google Scholar 

  • Steptoe PC, Edwards RG (1970) Laparoscopic recovery of preovulatory human oocytes after priming of ovaries with gonadotrophins. Lancet I:683–689

    Google Scholar 

  • Steptoe PC, Edwards RG (1976) Reimplantation of a human embryo with subsequent tubal pregnancy. Lancet I:880–882

    Google Scholar 

  • Steptoe PC, Edwards RG (1978) Birth after the reim- plantation of a human embryo. Lancet II: 366

    Article  Google Scholar 

  • Testart J, Frydman R (1982) Minimum time lapse between luteinizing hormone surge or human chorionic gonadotropin administration and follicular rupture. Fertil Steril 37: 50–53

    PubMed  CAS  Google Scholar 

  • Testart J, Frydman R, Feinstein MC, Thebault A, Roger M, Scholler R (1981) Interpretation of plasma luteinizing hormone assay for the collection of mature oocytes from women: definition of a luteinizing hormone surge-initiating rise. Fertil Steril 36: 50–54

    PubMed  CAS  Google Scholar 

  • Trotnow S, Kniewald T, Al-Hasani S, Becker H (1981) Follikelpunktion, In-vitro-Fertilisierung, Embryotransfer und eingetretene Schwangerschaften in Dyneric/HCG-stimulierten Zyklen. Geburtshilfe Frauenheilkd 41: 835–836

    Article  PubMed  CAS  Google Scholar 

  • Trotnow S, Kniewald T, Al-Hasani S, Becker H (1982a) Pregnancy after in vitro fertilization of an oocyte aspirated during tubal surgery. Arch Gynecol 231: 321–323

    Article  PubMed  CAS  Google Scholar 

  • Trotnow S, Becker H, Kniewald T, Al-Hasani S, Mulz D (1982b) Luteal phase following oocyte aspiration, in vitro fertilization, and embryo transfer in clomid/hCG-stimulated cycles. Arch Gynecol 231: 171–176

    Article  PubMed  CAS  Google Scholar 

  • Trotnow S, Al-Hasani S, Kniewald T, Becker H, Hünlich T (1983a) Transfer of human embryos at early cleavage stages. In: Beier HM, Lindner HR (eds) Fertilization of the human egg in vitro: biological basis and clinical applications. Springer, Berlin Heidelberg New York, pp 283–292

    Google Scholar 

  • Trotnow S, Al-Hasani S, Hünlich T, Schill WB (1983b) Bilateral tubal pregnancy following in vitro fertilization and embryo transfer. Arch Gynecol 234: 75–78

    Article  PubMed  CAS  Google Scholar 

  • Trotnow S, Kniewald T, Hünlich T (1983c) Die In-vitro-Fertilisation, ein neues Verfahren zur Sterilitätsbehandlung. Geburtshilfe Frauenheilkd 43: 1–6

    Article  PubMed  CAS  Google Scholar 

  • Trotnow S, Kniewald T, Hünlich T, Kreuzer E (1984a) Das Erlanger In-vitro-Fertilisationsprogramm–Bisherige Bilanz. Geburtshilfe Frauenheilkd 44: 375–380

    Article  PubMed  CAS  Google Scholar 

  • Trotnow S, Kniewald T, Hünlich T, Kreuzer E (1984b) Improvement of follicular puncture and oocyte recovery at Erlangen. Arch Gynecol 234: 205–212

    Article  PubMed  CAS  Google Scholar 

  • Trounson AO, Leeton JF, Wood C, Webb J, Kovacs G (1980) The investigation of idiopathic infertility by in vitro fertilization. Fertil Steril 34: 431–438

    PubMed  CAS  Google Scholar 

  • Trounson AO, Leeton JF, Wood C, et al (1981) A program of successful in vitro fertilization and embryo transfer in the controlled ovulatory cycle. In: Semm K, Mettler (eds) Human reproduction. Proceedings of the III. World congress. Excerpta Medica, Amsterdam, pp 173–180

    Google Scholar 

  • Trounson AO, Mohr LR, Wood C, Leeton JF (1982a) Effect of delayed insemination on in vitro fertilization, culture and transfer of human embryos. J Re-prod Fertil 64: 285–294

    Article  CAS  Google Scholar 

  • Trounson AO, Leeton JF, Wood C (1982b) In vitro fertilization and embryo transfer in the human. In: Rolland R, van Hall EV, Hillier SG, McNatty KP, Schoemaker J (eds) Follicular maturation and ovulation. Excerpta Medica, Amsterdam, pp 313–322 ( International Congress Series, No 560 )

    Google Scholar 

  • Veeck LL, Wortham JWE Jr, Witmyer J, Sandow BA, Acosta AA, Garcia JE, Jones GS, Jones HW Jr (1983) Maturation and fertilization of morphologically immature human oocytes in a program of in vitro fertilization. Fertil Steril 39: 594–602

    PubMed  CAS  Google Scholar 

  • Whitten WK (1956) Culture of tubal mouse ova. Nature 177: 96

    Article  PubMed  CAS  Google Scholar 

  • Whitten WK (1969) Effect of oxygen on cleavage of mouse eggs in vitro. Society for Study of Reproduction, 2nd ann meeting, Davis, Calif. Biol Re-prod Abstr, pp 29

    Google Scholar 

  • Whittingham DG (1968) Fertilization of mouse eggs in vitro. Nature 220: 592–593

    Article  PubMed  CAS  Google Scholar 

  • Wikland M, Nilson L, Hansson R, Hamberger L, Jansson PO (1983) Collection of human oocytes by the use of sonography. Fertil Steril 39: 603–608

    PubMed  CAS  Google Scholar 

  • Winston RML (1980) Microsurgery of the fallopian tube: from fantasy to reality. Fertil Steril 34:

    Google Scholar 

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Trotnow, S. (1987). In-vitro-Fertilisierung und Embryotransfer. In: Gynäkologische Endokrinologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71568-6_13

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  • DOI: https://doi.org/10.1007/978-3-642-71568-6_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71569-3

  • Online ISBN: 978-3-642-71568-6

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