Generation and Interpretation of Fast Atom Bombardment Mass Spectra of Modified Peptides
Until recently the possibility of mass spectrometric investigations was limited by the volatility of the investigated compounds. Due to the high polarity and low volatility of peptides, derivatization was necessary to obtain volatile derivatives, but new difficulties like incomplete reactions and/or side reactions and fragmentation were involved, and last but not least, the time needed for the derivatization was considerable.
KeywordsAmino Acid Analysis Cyclic Peptide Linear Peptide Fast Atom Bombardment Mass Spectrum MSMS Spectrum
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