Abstract
Genodermatoses with a marked sun sensitivity are very rare diseases in which the photosensitivity is an early and constant symptom. The photosensitivity can be expressed by sun-induced rashes of the exposed skin areas within hours and days or by light-induced tumor formation within years or by both symptom complexes together.
Preview
Unable to display preview. Download preview PDF.
References
Andrews AD, Barrett SF, Yoder FW, Robbins JH (1978) Cockayne’s syndrome fibroblasts have increased sensitivity to ultraviolet light but normal rates of unscheduled DNA synthesis. J Invest Dermatol 70:237–239
Chaganti RSK, Schonberg S, German J (1974) A manyfold increase in sister chromatid exchanges in Bloom’s syndrome lymphocytes. Proc Natl Acad Sci USA 71:4508–4512
Cleaver JE (1968) Defective repair replication of DNA in xeroderma pigmentosum. Nature 219:652–656
DeWeerd-Kastelein EA, Keijzer W, Bootsma D (1972) Genetic heterogeneity of xeroderma pigmentosum demonstrated by somatic cell hybridization. Nature 238:80–82
Dicken CH, Dewald G, Gordon H (1978) Sister chromatid exchanges in Bloom’s syndrome. Arch Dermatol 114:755–760
Fischer E, Thielmann HW, Neundörfer B, Rentsch FJ, Edler L, Jung EG (1982) Xeroderma pigmentosum patients from Germany: clinical symptoms and DNA repair characteristics. Arch Dermatol Res 274:229–247
Fischer E, Jung EG (1982) Photosensitivity and the genodermatoses. Semin Dermatol 1:169–174
Kraemer KH, Coon HG, Petinga RA, Barrett SF, Rahe AE, Robbins JH (1975) Genetic heterogeneity in xeroderma pigmentosum: complementation groups and their relationship to DNA repair rates. Proc Natl Acad Sci USA 72:95
Lischka G, Jung EG (1979) Lichtkrankheiten der Haut. Perimed, Erlangen
Wilcken B, Brown DA (1977) Natural history of Hartnup disease. Arch Dis Child 52:38–40
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Jung, E.G. (1987). Genodermatoses with Marked Photosensitivity. In: Happle, R., Grosshans, E. (eds) Pediatric Dermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71524-2_7
Download citation
DOI: https://doi.org/10.1007/978-3-642-71524-2_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-16991-8
Online ISBN: 978-3-642-71524-2
eBook Packages: Springer Book Archive