Eczema Therapy and Permeability of Infantile Skin for Topical Preparations

  • G. Stüttgen


This chapter is concerned with the question of whether the child’s skin provides a different prerequisite for locally applied substances than the adult skin and whether the conditions of the child’s skin are significant for therapeutic programming and also for the development of undesired accompanying phenomena. The skin of the child at various ages — from the fully developed newborn up to puberty — differs in many respects from that of the adult. Such differences are expressed in the anatomical data of the skin and its appending structures, biochemical data on the skin lipids, and finally biological data on the variable reactivity of the skin. These parameters are also reflected in the permeation behavior toward therapeutic substances in connection with eczema therapy.


Permeation Rate Caprylic Acid Percutaneous Absorption Biological Availability Topical Preparation 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • G. Stüttgen
    • 1
  1. 1.Hautklinik und Poliklinik, Rudolf-Virchow-KrankenhausFreie Universität BerlinBerlin 65Germany

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