Prospective Study of Serum VCA-IGA Antibody in the Normal Population in Guangdong Province of China
Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in the Guangdong province of China. It represents 31.5% of all malignant tumors based on the hospital registry in this province . A number of studies have demonstrated the higher serological reactivity to EBV-associated antigens among NPC patients compared with controls, independent of race and geography. Over 90% of NPC patients were positive for IgA antibodies to VCA at 1:10 dilution, as opposed to 0.6–6.0 in the control groups. GMTs of VCA-IgA were approximately 25-fold higher in NPC patients than in the various control groups . But how about the EBV serology reactivity for normal individuals? There is very little information on this aspect.
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