A Study of Tumor-Associated Antigens
The development of the hybridoma technique  has provided a powerful new tool for studies of tumor-associated antigens. Since 1978 Koprowski  and other investigators have prepared monoclonal antibodies (McAbs) to human melanoma, leukemia, lymphoma, colon cancer, breast cancer, lung cancer, and others. And some new tumor-associated antigens have been identified [4, 11]. However, there are only a few studies on antigens of gastric cancer. The mortality rate of gastric cancer is the highest one in China. Therefore, it is very interesting and necessary to investigate the antigens of gastric cancer in order to develop new approaches to the diagnosis and therapy of gastric cancer.
KeywordsGastric Cancer Gastric Cancer Cell MGC803 Cell Sodium Periodate Antigen Extract
Unable to display preview. Download preview PDF.
- 1.Atkins BF, Ernst CS, Herlyn M, Steplewski Z, Sears HF, Koprowski H: Gastrointestinal Cancer-associated Antigen in Immunoperoxidase Assay. Cancer Res. 43 (1982) 4820–4823Google Scholar
- 5.Dong ZW, Li ZP, Wan WH, Xu XL: Application of enzyme-linked immunofiltration to screening and characterization of monoclonal antibodies. Chin. J. Microbiol. Immunol. 5 (1985) 33–36Google Scholar