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Effects of Iloprost Treatment in the Rat on Prostacyclin Release from Isolated Aortas

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Prostacyclin and Its Stable Analogue Iloprost
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Abstract

The observation of an enhanced platelet reactivity after infusion of prostacyclin in clinical studies [1] suggests the possibility that the administration of this compound might inhibit the endogenous release of prostacyclin and, consequently, result in hyperactive platelets. In order to explore this possibility, we have studied the effects of acute and chronic administration of Iloprost in the rat, on the release of 6-keto-PGF from in vitro perfused aortas.

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References

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© 1987 Springer-Verlag, Berlin Heidelberg

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Masi, I., Giani, E., Mosconi, C., Galli, C. (1987). Effects of Iloprost Treatment in the Rat on Prostacyclin Release from Isolated Aortas. In: Gryglewski, R.J., Stock, G. (eds) Prostacyclin and Its Stable Analogue Iloprost. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71499-3_16

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  • DOI: https://doi.org/10.1007/978-3-642-71499-3_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71501-3

  • Online ISBN: 978-3-642-71499-3

  • eBook Packages: Springer Book Archive

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