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Multiwavelength Anomalous Diffraction in Protein Crystallography: Phase Calculations, Experimental Procedures and Results

  • R. Fourme
  • M. Chiadmi
  • R. Kahn
Conference paper
Part of the Springer Series in Biophysics book series (BIOPHYSICS, volume 2)

Abstract

Once suitable crystals have been grown, the phase problem- i. e. the determination of structure factor phases from Bragg reflection intensity data — remains the crucial difficulty of the ab-initio elucidation of any three-dimensional macromolecular structure by X-ray diffraction methods. The techniques which have been most commonly used to circumvent this problem have involved the special diffraction characteristics associated with the presence of a small number of heavy atoms which are either naturally present or purposely introduced in the parent structure of interest.

Keywords

Heavy Atom Bragg Reflection Joint Probability Distribution Acta Cryst Anomalous Dispersion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • R. Fourme
    • 1
  • M. Chiadmi
    • 1
  • R. Kahn
    • 1
  1. 1.LURE (CNRS, MEN & CEA) Université de Paris-SudOrsay CedexFrance

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