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Application of X-Ray Absorption Spectroscopy to the Investigation of Biological Calcification

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Biophysics and Synchrotron Radiation

Part of the book series: Springer Series in Biophysics ((BIOPHYSICS,volume 2))

Abstract

X-Ray absorption spectroscopy (XAS) has been widely used to characterise calcified deposits from biological systems [1,2] since the original experiments were performed [3,4]. Here we present a progress report with emphasis on selected aspects of our recent research. After the introduction to biological calcification, which forms this section and indicates why XAS is so useful for characterising the deposits, we summarise the principles of the technique so that its qualitative and, finally, its quantitative interpretation can be discussed in more detail.

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References

  1. S.S. Hasnain, Springer Proc. Phys. 2, 145–150 (1984).

    CAS  Google Scholar 

  2. D.W.L. Hukins, J.E. Harries and S.S. Hasnain, Biochem. Soc. Trans. 14, 545–549 (1986).

    PubMed  CAS  Google Scholar 

  3. R.M. Miller, D.W.L. Hukins, S.S. Hasnain and P. Lagarde, Biochem. Biophys. Res. Commun. 99, 102–106 (1981).

    Article  PubMed  CAS  Google Scholar 

  4. E.D. Eanes, L. Powers and J.L. Costa, Cell Calcium, 2, 251–261 (1981).

    Article  CAS  Google Scholar 

  5. A.L. Boskey, Clin. Orthop. 152, 225–257 (1981).

    Google Scholar 

  6. L.C. Bonar, M.D. Grynpas and M.J. Glimcher, J. Ultrastruct. Res. 86, 93–99 (1984).

    Article  PubMed  CAS  Google Scholar 

  7. J.E. Harries, J.S. Shah and S.S. Hasnain, Springer Proc. Phys. 2, 142–144 (1984).

    Google Scholar 

  8. A.J. Cox, J.E. Harries, D.W.L. Hukins, A.P. Kennedy and T.M. Sutton, Brit. J. Urol., in press.

    Google Scholar 

  9. G.N. Greaves, K. Simpkiss, M. Taylor and N. Binsted, Biochem. J. 221 855–868 (1984).

    PubMed  CAS  Google Scholar 

  10. M. Taylor, K. Simpkiss and G.N. Greaves, Biochem. Soc. Trans. 14, 549–552 (1986).

    PubMed  CAS  Google Scholar 

  11. R.I. Gibson, Amer. Mineral. 59, 1177–1182 (1974).

    CAS  Google Scholar 

  12. P. Einsenberger and B.M. Kincaid, Science, 200, 1441–1447 (1978).

    Article  Google Scholar 

  13. S.J. Gurman, J. Mater. Sci. 17 1541–1570 (1982).

    Article  CAS  Google Scholar 

  14. C. Holt, S.S. Hasnain and D.W.L. Hukins, Biochim. Biophys. Acta, 719, 299–303 (1982).

    Article  PubMed  CAS  Google Scholar 

  15. J.C. Irlam, C. Holt, S.S. Hasnain and D.W.L. Hukins, J. Dairy Res. 52, 267–273 (1985).

    Article  CAS  Google Scholar 

  16. J.C. Irlam, D.W.L. Hukins, C. Holt and S.S. Hasnain, Springer Proc. Phys. 2, 139–1141 (1984).

    CAS  Google Scholar 

  17. R.J.P. Williams, Symp. Soc. Exp. Biol. 30, 1–17 (1976).

    CAS  Google Scholar 

  18. G.H. Nancollas, in ‘Biological Mineralisation and Déminéralisation’, ed. G.H. Nancollas, pp. 79–99, Springer Verlag, Heidelberg, (1982).

    Google Scholar 

  19. J.E. Harries, W.J. My ring, C. Holt, D.W.L. Hukins, A. A. MacDowell and S.S. Hasnain, Biochem. Biophys. Res. Commun., submitted.

    Google Scholar 

  20. G.P. Diakun, G.N. Greaves, S.S. Hasnain and P.D. Quinn, SERC Daresbury Lab. Report DL/SCI/P507E (1986).

    Google Scholar 

  21. A. A. MacDowell, D. Norman and J.B. West, SERC Daresbury Lab. Report DL/SCI/P507E (1986)

    Google Scholar 

  22. P.A. Lee and J.B. Pendry, Phys. Rev. B11, 2795–2811 (1975).

    Article  CAS  Google Scholar 

  23. S.J. Gurman, N. Binsted and I. Ross, J. Phys. C, 17, 143–151 (1984).

    Article  CAS  Google Scholar 

  24. P.A. Lee, P.H. Citrin, P. Eisenberger and B.M. Kincaid, Rev. Mod. Phys. 53. 796–806 (1981).

    Article  Google Scholar 

  25. S.J. Gurman, N. Binsted and J. Ross, J. Phys. C, 19, 1845–1861 (1986).

    Article  Google Scholar 

  26. P.J. Durham, J.B. Pendry and C.H. Hodges, Comput. Phys. Commun. 25, 193–205 (1982).

    Article  CAS  Google Scholar 

  27. J.B. Pendry, ‘Low Energy Electron Diffraction’, Academic Press, New York, (1974).

    Google Scholar 

  28. D.E. Sayers, E.A. Stern and F.W. Lytle, Phys. Rev. Lett. 27, 1205–1207 (1971).

    Article  Google Scholar 

  29. J.E. Harries, D.W.L. Hukins and S.S. Hasnain, J. de Phys. C8–1181 (1986).

    Google Scholar 

  30. M.J. Kay, R.A. Young and A.S. Posner, Nature, 204, 1050–1052 (1964).

    Article  PubMed  CAS  Google Scholar 

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© 1987 Springer-Verlag Berlin Heidelberg

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Hukins, D.W.L., Harries, J.E. (1987). Application of X-Ray Absorption Spectroscopy to the Investigation of Biological Calcification. In: Bianconi, A., Congiu Castellano, A. (eds) Biophysics and Synchrotron Radiation. Springer Series in Biophysics, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71490-0_29

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  • DOI: https://doi.org/10.1007/978-3-642-71490-0_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71492-4

  • Online ISBN: 978-3-642-71490-0

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