Abstract
In this work we show that 1.) X-ray absorption studies of diferric chicken ovotransferrin (Fe2COT) provide evidence for direct water coordination at the metal binding sites. 2.) The immediate environment of the iron atoms appears unaltered as a function of pH when spectra are recorded in the non-chelating buffer MES. 3.) Studies on human serum transferrin provide no evidence for structural changes at the metal coordination sites as a consequence of proposed interdomain cooperativity.
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© 1987 Springer-Verlag Berlin Heidelberg
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Garratt, R., Evans, R., Hasnain, S., Lindley, P. (1987). The Interaction of Iron With Transferrins. In: Bianconi, A., Congiu Castellano, A. (eds) Biophysics and Synchrotron Radiation. Springer Series in Biophysics, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71490-0_21
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DOI: https://doi.org/10.1007/978-3-642-71490-0_21
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