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Effects of a Single Oral Dose of Milrinone on Left Ventricular Systolic Performance

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Vasoaktive Substanzen bei Herzinsuffizienz

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Abstract

The introduction of the cardiac bipyridines into the pharmacotherapy of congestive heart failure marked the beginning of innovative research in this area of cardiovascular pharmacology [1, 5, 6]. The forerunner of this new group of compounds was amrinone, which has been proved effective both intravenously [10] and orally [11] in treating congestive heart failure. The limitation of this drug is the high incidence, after long-term oral therapy, of gastrointestinal side effects, thrombocytopenia, and fever [11, 18].

Dr. Piscione is supported by CNR-NATO research fellowship no. 216, 1095

Dr. Jeski is supported by National Institute of Health Traing Grant 5-T32-HLO-7049

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Author information

Authors and Affiliations

  1. Thoraxcentre, Erasmus University Rotterdam, P.O.Box 1738, NL-3000 DR, Rotterdam, The Netherlands

    F. Piscione

Authors
  1. F. Piscione
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  2. B. E. Jaski
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  3. P. W. Serruys
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Editor information

Editors and Affiliations

  1. Zentrum der Inneren Medizin, Abteilung für Kardiologie, Klinikum der Johann-Wolfgang-Goethe Universität, Theodor-Stern-Kai 7, D-6000, Frankfurt, Germany

    Wulf-Dirk Bussmann

  2. Innere Medizin III, Medizinische Universitätsklinik, Hugstetter Str. 55, D-7800, Freiburg i. Br., Germany

    H. Just

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© 1986 Springer-Verlag Berlin Heidelberg

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Piscione, F., Jaski, B.E., Serruys, P.W. (1986). Effects of a Single Oral Dose of Milrinone on Left Ventricular Systolic Performance. In: Bussmann, WD., Just, H. (eds) Vasoaktive Substanzen bei Herzinsuffizienz. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71486-3_34

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  • DOI: https://doi.org/10.1007/978-3-642-71486-3_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16946-8

  • Online ISBN: 978-3-642-71486-3

  • eBook Packages: Springer Book Archive

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