Effects of Nifedipine in Congestive Heart Failure Due to Dilated Cardiomyopathy: A Randomized, Double-Blind, Cross-over Study
On the basis of its vasodilatory properties, the calcium channel blocker nifedipine has been recommended and employed for the treatment of congestive heart failure [1–4]. Promising initial reports indicated favorable hemodynamic effects, but with no evidence of a negative inotropic action. These early studies, however, were carried out in heterogeneous groups of patients with respect to the etiology of heart failure, in which, conspicuously, coronary artery disease predominated.
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- 3.Matsumoto S, Ito T, Sada T (1980) Hemodynamic effects of nifedipine in congestive heart failure. Am J Cardiol 46: 478–480Google Scholar