Advertisement

Effects of Nifedipine in Congestive Heart Failure Due to Dilated Cardiomyopathy: A Randomized, Double-Blind, Cross-over Study

  • D. Hall
  • K. L. Froer
  • F. Kraus
  • C. Stautner
  • W. Rudolph
Conference paper

Abstract

On the basis of its vasodilatory properties, the calcium channel blocker nifedipine has been recommended and employed for the treatment of congestive heart failure [1–4]. Promising initial reports indicated favorable hemodynamic effects, but with no evidence of a negative inotropic action. These early studies, however, were carried out in heterogeneous groups of patients with respect to the etiology of heart failure, in which, conspicuously, coronary artery disease predominated.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Ludbrook P, Tiefenbrun A, Sobel B (1982) Acute hemodynamic responses to sublingual nifedipine: dependence on left ventricular function. Circulation 65: 489–492PubMedCrossRefGoogle Scholar
  2. 2.
    Klugmann S, Salvi A, Camerini F (1980) Hemodynamic effects of nifedipine in heart failure. Br Heart J 43: 440–446PubMedCrossRefGoogle Scholar
  3. 3.
    Matsumoto S, Ito T, Sada T (1980) Hemodynamic effects of nifedipine in congestive heart failure. Am J Cardiol 46: 478–480Google Scholar
  4. 4.
    Polese A, Fioretini C, Olivari M, Guazzi M (1979) Clinical use of a calcium antagonist (nifedipine) in acute pulmonary edema. Am J Med 66: 825–830PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • D. Hall
    • 1
  • K. L. Froer
  • F. Kraus
  • C. Stautner
  • W. Rudolph
  1. 1.Deutsches HerzzentrumMünchen 11Germany

Personalised recommendations